In vitro granulocyte migration from bone marrow, tissues and blood vessels in atopic patients.

An examination of the migration ability of pool tissue and vascular granulocytes was performed in 60 patients and in 9 patients, the migration ability of bone marrow granulocytes. The test for granulocyte migration by Clausen, Bendixen and Søborg was performed with each granulocyte pool separately. It was proved that in patients with atopic asthma there is a significant statistical reduction in bone marrow and peripheral blood granulocyte migration during the asymptomatic period. During dyspnea, a decrease in migration of granulocytes from tissue and peripheral blood is seen.