肺动脉增粗与中重度 COPD 患者的死亡风险：COPDGene 研究结果。
Pulmonary artery enlargement and mortality risk in moderate to severe COPD: results from COPDGene.
机构信息
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA
UAB Lung Health Center, Birmingham, AL, USA.
出版信息
Eur Respir J. 2020 Feb 12;55(2). doi: 10.1183/13993003.01812-2019. Print 2020 Feb.
Abstract
Pulmonary artery enlargement on chest CT imaging is independently associated with all-cause mortality in moderate-severe COPD, after adjustment for other known risk factors for COPD mortality and cardiovascular disease.
摘要
胸部 CT 成像显示肺动脉增大与中重度 COPD 的全因死亡率独立相关，在调整 COPD 死亡率和心血管疾病的其他已知危险因素后。
相似文献
1
Pulmonary artery enlargement and mortality risk in moderate to severe COPD: results from COPDGene.肺动脉增粗与中重度 COPD 患者的死亡风险：COPDGene 研究结果。
Eur Respir J. 2020 Feb 12;55(2). doi: 10.1183/13993003.01812-2019. Print 2020 Feb.
2
Clinical, physiologic, and radiographic factors contributing to development of hypoxemia in moderate to severe COPD: a cohort study.导致中重度慢性阻塞性肺疾病患者低氧血症发生的临床、生理及影像学因素：一项队列研究
BMC Pulm Med. 2016 Dec 1;16(1):169. doi: 10.1186/s12890-016-0331-0.
3
Pulmonary Artery Enlargement Is Associated With Cardiac Injury During Severe Exacerbations of COPD.慢性阻塞性肺疾病严重加重期肺动脉扩张与心脏损伤有关。
Chest. 2016 May;149(5):1197-204. doi: 10.1378/chest.15-1504. Epub 2016 Jan 12.
4
Relationship between chronic obstructive pulmonary disease and subclinical coronary artery disease in long-term smokers.长期吸烟与慢性阻塞性肺疾病和亚临床冠状动脉疾病的关系。
Eur Heart J Cardiovasc Imaging. 2013 Dec;14(12):1159-66. doi: 10.1093/ehjci/jet057. Epub 2013 May 2.
5
Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease.严重早发型慢性阻塞性肺疾病的外显子组测序分析
Am J Respir Crit Care Med. 2016 Jun 15;193(12):1353-63. doi: 10.1164/rccm.201506-1223OC.
6
Impact of chronic obstructive pulmonary disease severity on surgical outcomes in patients undergoing non-emergent coronary artery bypass grafting.慢性阻塞性肺疾病严重程度对非紧急冠状动脉旁路移植术患者手术结局的影响。
Eur J Cardiothorac Surg. 2012 Jul;42(1):108-13; discussion 113. doi: 10.1093/ejcts/ezr271. Epub 2012 Jan 22.
7
CT measurements of central pulmonary vasculature as predictors of severe exacerbation in COPD.慢性阻塞性肺疾病（COPD）中中央肺血管的CT测量作为严重加重的预测指标
Medicine (Baltimore). 2018 Jan;97(3):e9542. doi: 10.1097/MD.0000000000009542.
8
MicroRNA Dysregulation in Pulmonary Arteries from Chronic Obstructive Pulmonary Disease. Relationships with Vascular Remodeling.慢性阻塞性肺疾病肺动脉中 microRNA 的失调。与血管重构的关系。
Am J Respir Cell Mol Biol. 2018 Oct;59(4):490-499. doi: 10.1165/rcmb.2017-0040OC.
9
Pulmonary artery to aorta ratio and risk of all-cause mortality in the general population: the Rotterdam Study.肺动脉与主动脉比值与普通人群全因死亡率的关系：鹿特丹研究。
Eur Respir J. 2017 Jun 15;49(6). doi: 10.1183/13993003.02168-2016. Print 2017 Jun.
10
Omics and the Search for Blood Biomarkers in Chronic Obstructive Pulmonary Disease. Insights from COPDGene.组学与慢性阻塞性肺疾病血液生物标志物的研究：COPDGene 的启示。
Am J Respir Cell Mol Biol. 2019 Aug;61(2):143-149. doi: 10.1165/rcmb.2018-0245PS.
引用本文的文献
1
The prognostic value of the TAPSE/PASP ratio in lung transplant candidates.TAPSE/PASP比值在肺移植候选者中的预后价值。
Turk Gogus Kalp Damar Cerrahisi Derg. 2025 Apr 30;33(2):165-175. doi: 10.5606/tgkdc.dergisi.2025.26847. eCollection 2025 Apr.
2
Leveraging Computed Tomography Imaging to Detect Chronic Obstructive Pulmonary Disease and Concomitant Chronic Diseases.利用计算机断层扫描成像检测慢性阻塞性肺疾病及合并的慢性疾病。
Am J Respir Crit Care Med. 2024 Aug 1;210(3):281-287. doi: 10.1164/rccm.202402-0407PP.
3
Prevalence of pulmonary artery dilation in non-cystic fibrosis bronchiectasis: a computed tomography analysis from a cohort of the US Bronchiectasis and Nontuberculous Mycobacteria Research Registry.非囊性纤维化支气管扩张症中肺动脉扩张的患病率：来自美国支气管扩张症和非结核分枝杆菌研究注册队列的计算机断层扫描分析
J Thorac Dis. 2024 Feb 29;16(2):1496-1502. doi: 10.21037/jtd-23-1316. Epub 2024 Feb 27.
4
COPD in People with HIV: Epidemiology, Pathogenesis, Management, and Prevention Strategies.HIV 感染者中的 COPD：流行病学、发病机制、管理和预防策略。
Int J Chron Obstruct Pulmon Dis. 2023 Nov 29;18:2795-2817. doi: 10.2147/COPD.S388142. eCollection 2023.
5
The association between pulmonary artery enlargement and mortality in an Emergency Department population undergoing computed tomography pulmonary angiography.在接受计算机断层扫描肺动脉造影的急诊科患者中，肺动脉增大与死亡率之间的关联。
Pulm Circ. 2023 Apr 1;13(2):e12225. doi: 10.1002/pul2.12225. eCollection 2023 Apr.
6
Diagnostic value of computed tomography-based pulmonary artery to aorta ratio measurement in chronic obstructive pulmonary disease with pulmonary hypertension: A systematic review and meta-analysis.基于 CT 的肺动脉与主动脉比值测量在合并肺动脉高压的慢性阻塞性肺疾病中的诊断价值：系统评价和荟萃分析。
Clin Respir J. 2022 Apr;16(4):276-283. doi: 10.1111/crj.13485. Epub 2022 Mar 14.
7
Chest CT-assessed comorbidities and all-cause mortality risk in COPD patients in the BODE cohort.BODE 队列中 COPD 患者的胸部 CT 评估合并症与全因死亡率风险。
Respirology. 2022 Apr;27(4):286-293. doi: 10.1111/resp.14223. Epub 2022 Feb 7.
8
Functional imaging of COPD by CT and MRI.CT 和 MRI 对 COPD 的功能成像。
Br J Radiol. 2022 Apr 1;95(1132):20201005. doi: 10.1259/bjr.20201005. Epub 2021 Sep 19.
9
Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation.肺移植候选人选择的共识文件：国际心肺移植学会的更新。
J Heart Lung Transplant. 2021 Nov;40(11):1349-1379. doi: 10.1016/j.healun.2021.07.005. Epub 2021 Jul 24.
10
Pulmonary Artery Enlargement Is Associated with Exacerbations and Mortality in Ever-Smokers with Preserved Ratio Impaired Spirometry.肺动脉增大与肺功能比值保留但肺活量降低的既往吸烟者的病情加重及死亡率相关。
Am J Respir Crit Care Med. 2021 Aug 15;204(4):481-485. doi: 10.1164/rccm.202103-0619LE.
本文引用的文献
1
Mortality and Exacerbations by Global Initiative for Chronic Obstructive Lung Disease Groups ABCD: 2011 Versus 2017 in the COPDGene® Cohort.慢性阻塞性肺疾病全球倡议ABCD组的死亡率和急性加重情况：COPDGene®队列中2011年与2017年对比
Chronic Obstr Pulm Dis. 2019 Jan 10;6(1):64-73. doi: 10.15326/jcopdf.6.1.2018.0130.
2
Pulmonary arterial enlargement predicts long-term survival in COPD patients.肺动脉增宽可预测 COPD 患者的长期生存。
PLoS One. 2018 Apr 25;13(4):e0195640. doi: 10.1371/journal.pone.0195640. eCollection 2018.
3
Pulmonary artery to aorta ratio and risk of all-cause mortality in the general population: the Rotterdam Study.肺动脉与主动脉比值与普通人群全因死亡率的关系：鹿特丹研究。
Eur Respir J. 2017 Jun 15;49(6). doi: 10.1183/13993003.02168-2016. Print 2017 Jun.
4
Clinical, physiologic, and radiographic factors contributing to development of hypoxemia in moderate to severe COPD: a cohort study.导致中重度慢性阻塞性肺疾病患者低氧血症发生的临床、生理及影像学因素：一项队列研究
BMC Pulm Med. 2016 Dec 1;16(1):169. doi: 10.1186/s12890-016-0331-0.
5
Pulmonary Artery Enlargement Is Associated With Cardiac Injury During Severe Exacerbations of COPD.慢性阻塞性肺疾病严重加重期肺动脉扩张与心脏损伤有关。
Chest. 2016 May;149(5):1197-204. doi: 10.1378/chest.15-1504. Epub 2016 Jan 12.
6
Pulmonary artery enlargement is associated with right ventricular dysfunction and loss of blood volume in small pulmonary vessels in chronic obstructive pulmonary disease.肺动脉扩大与慢性阻塞性肺疾病中右心室功能障碍及小肺血管血容量减少有关。
Circ Cardiovasc Imaging. 2015 Apr;8(4). doi: 10.1161/CIRCIMAGING.114.002546.
7
Global and regional trends in COPD mortality, 1990-2010.1990 - 2010年慢性阻塞性肺疾病死亡率的全球及区域趋势
Eur Respir J. 2015 May;45(5):1239-47. doi: 10.1183/09031936.00142414. Epub 2015 Apr 2.
8
Pulmonary artery size as a predictor of pulmonary hypertension and outcomes in patients with chronic obstructive pulmonary disease.肺动脉大小作为慢性阻塞性肺疾病患者肺动脉高压及预后的预测指标
Respir Med. 2014 Nov;108(11):1626-32. doi: 10.1016/j.rmed.2014.08.009. Epub 2014 Sep 2.
9
IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease.IREB2和GALC与慢性阻塞性肺疾病中的肺动脉增大有关。
Am J Respir Cell Mol Biol. 2015 Mar;52(3):365-76. doi: 10.1165/rcmb.2014-0210OC.
10
CT scan-measured pulmonary artery to aorta ratio and echocardiography for detecting pulmonary hypertension in severe COPD.CT 扫描测量的肺动脉与主动脉比值和超声心动图用于检测严重 COPD 中的肺动脉高压。
Chest. 2014 Apr;145(4):824-832. doi: 10.1378/chest.13-1422.
Zotero 插件