手术减瘤对卵巢癌患者化疗反应的影响。
The effect of surgical debulking on the response of patients with ovarian carcinoma to chemotherapy.
作者信息
McDermott D F, Jaffe E A, Coleman M, Pasmantier M W
机构信息
Department of Medicine, Cornell University Medical College, New York, New York.
出版信息
Am J Clin Oncol. 1988 Oct;11(5):520-3. doi: 10.1097/00000421-198810000-00002.
Abstract
The role of debulking surgery as an adjuvant to chemotherapy in advanced ovarian carcinoma was examined. Debulking surgery did not alter the overall response rate to chemotherapy. Surgical resection, though, was associated with an increased percentage of complete pathological remissions, particularly in patients receiving efficacious chemotherapy. Whether debulking surgery is causal or a prognostic factor remains conjectural.
摘要
研究了肿瘤细胞减灭术作为晚期卵巢癌化疗辅助手段的作用。肿瘤细胞减灭术并未改变化疗的总体缓解率。然而，手术切除与完全病理缓解率的提高相关，尤其是在接受有效化疗的患者中。肿瘤细胞减灭术是病因还是预后因素仍不确定。
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