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在冠心病患者中,3 年内不同的痛苦症状轨迹与基线疾病认知有关。

Distinct Distress Symptom Trajectories Over 3 Years Are Associated With Baseline Illness Perceptions in Individuals With Coronary Heart Disease.

机构信息

Health Psychology Section, Psychology Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London Bridge, London, UK.

Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

出版信息

Ann Behav Med. 2020 Apr 20;54(5):374-379. doi: 10.1093/abm/kaz054.

Abstract

BACKGROUND

Depression and anxiety symptoms (termed distress) are common among coronary heart disease (CHD) patients and associated with poor outcomes. Illness perceptions predict distinct outcome trajectories in other long-term conditions, yet it is not known how they relate to distress trajectories in CHD.

PURPOSE

This study aimed to examine whether baseline illness perceptions are associated with distress symptom trajectories among primary care CHD patients.

METHODS

This is a secondary analysis of 803 CHD patients from the UPBEAT-UK study, who completed the Hospital Anxiety and Depression Scale every 6 months for 3 years. Baseline assessments included the Brief Illness Perception Questionnaire. Using latent class growth analysis, Palacios et al. (2018) identified five distinct distress symptom trajectories ("stable low," "chronic high," "improving," "worsening," and "fluctuating") in this cohort. Adjusted multinomial logistic regression analyses were used to test the association between baseline illness perceptions and distress symptom trajectories.

RESULTS

Compared with the stable low distress trajectory, stronger illness identity (odds ratio [OR] = 1.31, p < .01), higher perceived consequences (OR = 1.47, p < .01), illness-related emotion (OR = 1.66, p < .01), and illness concerns (OR = 1.36, p < .01) increased the odds of having chronic high distress. Stronger illness coherence (OR = 0.89, p < .05) and personal (OR = 0.77, p < .01) and treatment control (OR = 0.75, p < .01) reduced the odds of chronic high distress. Worsening distress symptoms were associated with weaker perceptions of treatment control, higher perceived consequences, and greater illness-related concerns and emotions.

CONCLUSIONS

Illness perceptions of CHD are associated with distress symptom trajectories. Therapeutically modifying unhelpful illness perceptions in CHD patients who experience high levels of distress could potentially improve mental health outcomes.

摘要

背景

抑郁和焦虑症状(称为困扰)在冠心病(CHD)患者中很常见,并且与不良结局相关。在其他长期疾病中,疾病认知预测了不同的结局轨迹,但尚不清楚它们与 CHD 患者的困扰轨迹有何关系。

目的

本研究旨在检验基线疾病认知是否与初级保健 CHD 患者的困扰症状轨迹相关。

方法

这是 UPBEAT-UK 研究中 803 例 CHD 患者的二次分析,这些患者在 3 年内每 6 个月完成一次医院焦虑和抑郁量表。基线评估包括简短疾病认知问卷。使用潜在类别增长分析,Palacios 等人(2018 年)在该队列中确定了五种不同的困扰症状轨迹(“稳定低”、“慢性高”、“改善”、“恶化”和“波动”)。调整后的多项逻辑回归分析用于检验基线疾病认知与困扰症状轨迹之间的关联。

结果

与稳定的低困扰轨迹相比,更强的疾病认同(比值比 [OR] = 1.31,p <.01)、更高的感知后果(OR = 1.47,p <.01)、与疾病相关的情绪(OR = 1.66,p <.01)和疾病担忧(OR = 1.36,p <.01)增加了患有慢性高困扰的几率。更强的疾病一致性(OR = 0.89,p <.05)和个人(OR = 0.77,p <.01)和治疗控制(OR = 0.75,p <.01)降低了慢性高困扰的几率。困扰症状恶化与治疗控制、感知后果更高以及与疾病相关的担忧和情绪更大有关。

结论

CHD 的疾病认知与困扰症状轨迹相关。在经历高水平困扰的 CHD 患者中,治疗性地改变不良的疾病认知可能会改善心理健康结局。

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