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激光拉曼光谱法揭示的中耳胆脂瘤导致骨破坏的机制

Mechanism of bone destruction due to middle ear cholesteatoma as revealed by laser-Raman spectrometry.

作者信息

Ohsaki K, Yamashita S, Fujita A, Masuda Y, Ueda S, Sugiura T, Tamura K, Shibata A

机构信息

Division of Clinical Otology, University Hospital, School of Medicine, Tokushima University, Japan.

出版信息

Am J Otolaryngol. 1988 May-Jun;9(3):117-26. doi: 10.1016/s0196-0709(88)80017-6.

DOI:10.1016/s0196-0709(88)80017-6
PMID:3177765
Abstract

In an investigation of the mechanism of bone destruction caused by chronic otitis media complicated with cholesteatoma, both the processes of demineralization and remineralization were studied in an animal model and clinically at the molecular level, using a laser-Raman spectrometer. From this investigation, it is proposed that the mechanism of bone destruction associated with cholesteatoma is a form of demineralization.

摘要

在一项关于慢性中耳炎合并胆脂瘤所致骨质破坏机制的研究中,利用激光拉曼光谱仪,在动物模型和临床分子水平上对脱矿质和再矿化过程进行了研究。通过这项研究,有人提出与胆脂瘤相关的骨质破坏机制是一种脱矿质形式。

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Mechanism of bone destruction due to middle ear cholesteatoma as revealed by laser-Raman spectrometry.激光拉曼光谱法揭示的中耳胆脂瘤导致骨破坏的机制
Am J Otolaryngol. 1988 May-Jun;9(3):117-26. doi: 10.1016/s0196-0709(88)80017-6.
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