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孤立性小指远侧指间关节掌腱膜挛缩症

Isolated Small Finger Distal Interphalangeal Joint Dupuytren's Contracture.

作者信息

Mehdi Syed K, King John D, Keshtvarz Sara, Kamineni Srinath, Dhawan Vikas

机构信息

University of Kentucky Department of Orthopedic Surgery and Sports Medicine, Lexington, Kentucky, USA.

University of Kentucky College of Medicine, Lexington Kentucky, USA.

出版信息

Case Rep Orthop. 2019 Nov 4;2019:7183739. doi: 10.1155/2019/7183739. eCollection 2019.

Abstract

Dupuytren's contracture is a disease involving abnormal myofibroblast proliferation and collagen deposition leading to the formation of pathologic cords in the hand. Given that Dupuytren's contractures rarely extend to the distal interphalangeal joint (DIP), affecting only 5% of patients, there are few cases reported in the literature. Collagenase injection is a frequently used option for minimally invasive treatment of Dupuytren's disease with greater than a 20-degree joint contracture. Unfortunately, there is limited research on the effectiveness of these injections in isolated DIP joint deformities. We present a case of a 61-year-old right hand-dominant male with a 2-year history of isolated right small finger Dupuytren's contracture at the DIP joint who achieved significant improvement after collagenase injection.

摘要

掌腱膜挛缩症是一种涉及异常肌成纤维细胞增殖和胶原沉积的疾病,会导致手部形成病理性条索。鉴于掌腱膜挛缩症很少延伸至远端指间关节(DIP),仅影响5%的患者,文献中报道的病例很少。胶原酶注射是治疗关节挛缩大于20度的掌腱膜挛缩症的常用微创治疗方法。不幸的是,关于这些注射剂对孤立性DIP关节畸形有效性的研究有限。我们报告一例61岁右利手男性患者,其右小指DIP关节孤立性掌腱膜挛缩症病史2年,胶原酶注射后取得显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fd0/6875190/1268e31982ad/CRIOR2019-7183739.001.jpg

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