Hauser R A, Lacey D M, Knight M R
Department of Neurology, Medical College of Hampton Roads, Norfolk, VA 23507.
Arch Neurol. 1988 Oct;45(10):1078-83. doi: 10.1001/archneur.1988.00520340032007.
Computed tomographic (CT) and magnetic resonance imaging (MRI) views of the brain were obtained in two adults and one child with hypertensive encephalopathy (HTE). Noncontrast CT was normal in one case and demonstrated decreased density posteriorly in two cases; MRI demonstrated focal, symmetric increased signal intensity in white matter and cortex, with occipital lobe involvement in each case. These lesions were better visualized on T2-weighted than on spin density images and were resolved on follow-up MRI four to five weeks later. These MRI studies support the concept that HTE is caused by the multifocal extravasation of fluid and proteins across the blood-brain barrier during "breakthrough" of cerebral autoregulation. We found that MRI appears more sensitive than CT and better defines the anatomy of cerebral involvement in HTE.
对两名成人和一名患有高血压脑病（HTE）的儿童进行了脑部计算机断层扫描（CT）和磁共振成像（MRI）检查。其中一例非增强CT检查结果正常，两例显示后部密度降低；MRI显示白质和皮质出现局灶性、对称性信号强度增加，每例均累及枕叶。这些病变在T2加权图像上比在自旋密度图像上显示得更清晰，在4至5周后的随访MRI中消失。这些MRI研究支持了这样一种观点，即高血压脑病是由于在脑自动调节“突破”期间，液体和蛋白质通过血脑屏障多灶性外渗所致。我们发现，MRI似乎比CT更敏感，能更好地明确高血压脑病中脑部受累的解剖结构。
