Kuzan-Fischer Claudia M, Souweidane Mark M
Departments of1Neurological Surgery and.
2Pediatrics, Weill Cornell Medical College, NewYork-Presbyterian Hospital, New York; and.
J Neurosurg Pediatr. 2019 Dec 1;24(6):611-621. doi: 10.3171/2019.5.PEDS18376.
An invited article highlighting diffuse intrinsic pontine glioma (DIPG) to celebrate the 75th Anniversary of the Journal of Neurosurgery, a journal known to define surgical nuance and enterprise, is paradoxical since DIPG has long been relegated to surgical abandonment. More recently, however, the neurosurgeon is emerging as a critical stakeholder given our role in tissue sampling, collaborative scientific research, and therapeutic drug delivery. The foundation for this revival lies in an expanding reliance on tissue accession for understanding tumor biology, available funding to fuel research, and strides with interventional drug delivery.
一篇特邀文章着重介绍弥漫性脑桥内生型胶质瘤（DIPG），以庆祝《神经外科杂志》创刊75周年，这本杂志以定义手术细节和事业而闻名，这颇具矛盾性，因为DIPG长期以来一直被视为手术禁区。然而，最近，鉴于神经外科医生在组织采样、合作科研及治疗性药物递送方面所起的作用，神经外科医生正成为关键利益相关者。这种复兴的基础在于越来越依赖获取组织来了解肿瘤生物学、有可用资金推动研究以及在介入性药物递送方面取得的进展。
