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老年患者横结肠癌腹腔镜结肠切除术的手术及生存结果

Surgical and survival outcomes of laparoscopic colectomy for trans-verse colon cancer in elderly patients.

作者信息

Yue Meng, Wang Yue, Kang Zhen Hua, Wang Xu, Wang Lei

机构信息

Department of Colorectal and Anal Surgery, the First Hospital of Jilin University, Changchun 130012, Jilin, People's Republic of China.

出版信息

J BUON. 2019 Sep-Oct;24(5):1852-1860.

Abstract

PURPOSE

This study was designed to compare the survival and surgical outcomes of laparoscopic colectomy (LC) in elderly and non-elderly patients with transverse colon cancer (TCC).

METHODS

From January 2011 to January 2018, 44 elderly (aged ≥70 years) and 72 non-elderly (aged <70 years) patients with TCC underwent LC at our institution. The survival and surgical outcomes of the two groups were compared retrospectively.

RESULTS

Preoperatively, the Charlson Comorbidity Index (CCI) and American Society of Anesthesiologists score were higher in the elderly group than in the non-elderly group. There were no significant differences between the groups in operating time, intraoperative blood loss, conversion rate, pathologic data, 30-day postoperative mortality rate, incidence of 30-day postoperative complications, incidence of major complications, or compliance with adjuvant chemotherapy. During the follow-up period, differences in recurrence rate, 5-year overall survival (OS) rate, and 5-year disease-free survival (DFS) rate between the groups were not significant.

CONCLUSION

Although elderly patients with TCC have higher surgical risk than non-elderly patients, performing LC in elderly patients is safe and effective. The survival and surgical outcomes in elderly patients were similar to those in non-elderly patients.

摘要

目的

本研究旨在比较老年和非老年横结肠癌(TCC)患者行腹腔镜结肠切除术(LC)后的生存率和手术效果。

方法

2011年1月至2018年1月,我院对44例老年(年龄≥70岁)和72例非老年(年龄<70岁)TCC患者实施了LC。对两组患者的生存率和手术效果进行回顾性比较。

结果

术前,老年组的查尔森合并症指数(CCI)和美国麻醉医师协会评分高于非老年组。两组在手术时间、术中出血量、中转率、病理数据、术后30天死亡率、术后30天并发症发生率、主要并发症发生率或辅助化疗依从性方面无显著差异。在随访期间,两组之间的复发率、5年总生存率(OS)和5年无病生存率(DFS)差异不显著。

结论

虽然老年TCC患者的手术风险高于非老年患者,但对老年患者实施LC是安全有效的。老年患者的生存和手术效果与非老年患者相似。

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