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青少年和年轻成年人的腰椎间盘突出症手术:长期结果比较。

Lumbar disc herniation surgery in adolescents and young adults: a long-term outcome comparison.

机构信息

Department of Clinical Science, Intervention and Technology, Division of Orthopedics and Biotechnology, Karolinska Institutet, Stockholm, Sweden.

Department of Reconstructive Orthopedics, Karolinska University Hospital, Stockholm, Sweden.

出版信息

Bone Joint J. 2019 Dec;101-B(12):1534-1541. doi: 10.1302/0301-620X.101B12.BJJ-2019-0621.R1.

Abstract

AIMS

The purpose of this study was to investigate the risk of additional surgery in the lumbar spine and to describe long-term changes in patient-reported outcomes after surgery for lumbar disc herniation in adolescents and young adults.

PATIENTS AND METHODS

We conducted a retrospective study design on prospectively collected data from a national quality register. The 4537 patients were divided into two groups: adolescents (≤ 18 years old, n = 151) and young adults (19 to 39 years old, n = 4386). The risk of additional lumbar spine surgery was surveyed for a mean of 11.4 years (6.0 to 19.3) in all 4537 patients. Long-term patient-reported outcomes were available at a mean of 7.2 years (5.0 to 10.0) in up to 2716 patients and included satisfaction, global assessment for leg and back pain, Oswestry Disability Index, visual analogue scale for leg and back pain, EuroQol five-dimension questionnaire (EQ-5D), and 36-Item Short-Form Health Survey (SF-36) Mental Component Summary and Physical Component Summary scores. Statistical analyses were performed with Cox proportional hazard regression, chi-squared test, McNemar's test, Welch-Satterthwaite -test, and Wilcoxon's signed-rank test.

RESULTS

Any type of additional lumbar spine surgery was seen in 796 patients (18%). Surgery for lumbar disc herniation accounted for more than half of the additional surgeries. The risk of any additional surgery was 0.9 (95% confidence interval (CI) 0.6 to 1.4) and the risk of additional lumbar disc herniation surgery was 1.0 (0.6 to 1.7) in adolescents compared with the young adult group. Both age groups improved their patient-reported outcome data after surgery (all p < 0.001). Changes between short- (mean 1.9 years (1.0 to 2.0)) and long-term follow-up (mean 7.2 years (5.0 to 10.0)) were small.

CONCLUSION

The risk of any additional lumbar spine surgery and additional lumbar disc herniation surgery was similar in adolescents and young adults. All patient-reported outcomes improved from preoperative to the short-term follow-up, while no likely clinically important differences between the short- and long-term follow-up were seen within both groups. Cite this article: 2019;101-B:1534-1541.

摘要

目的

本研究旨在探讨青少年和年轻成年人腰椎间盘突出症手术后腰椎再次手术的风险,并描述手术治疗后患者报告结局的长期变化。

患者与方法

我们对全国质量登记处前瞻性收集的数据进行了回顾性研究设计。4537 例患者分为两组:青少年组(≤18 岁,n=151)和年轻成人组(19-39 岁,n=4386)。对所有 4537 例患者平均随访 11.4 年(6.0-19.3),调查再次腰椎手术的风险。多达 2716 例患者的长期患者报告结局在平均 7.2 年(5.0-10.0)时可用,包括满意度、腿部和背部疼痛的总体评估、Oswestry 残疾指数、腿部和背部疼痛的视觉模拟量表、EuroQol 五维问卷(EQ-5D)和 36 项简明健康调查问卷(SF-36)精神成分综合评分和生理成分综合评分。采用 Cox 比例风险回归、卡方检验、McNemar 检验、Welch-Satterthwaite 检验和 Wilcoxon 符号秩检验进行统计学分析。

结果

796 例(18%)患者行任何类型的再次腰椎手术。腰椎间盘突出症手术占再次手术的一半以上。与年轻成人组相比,青少年组再次手术的风险为 0.9(95%置信区间[CI]0.6-1.4),再次腰椎间盘突出症手术的风险为 1.0(0.6-1.7)。两组患者术后患者报告结局数据均有所改善(均 p<0.001)。短期(平均 1.9 年[1.0-2.0])和长期随访(平均 7.2 年[5.0-10.0])之间的变化较小。

结论

青少年和年轻成年人再次腰椎手术和再次腰椎间盘突出症手术的风险相似。所有患者报告结局均从术前改善至短期随访,两组患者短期和长期随访之间未见可能具有临床重要意义的差异。

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