Rock M G
Division of Orthopedic Surgery, University Hospital, London, Ont.
Can J Surg. 1988 Nov;31(6):385-9.
Soft-tissue sarcomas account for only 1% of all malignant lesions. The Canadian Sarcoma Group encourages the investigation and management of these tumours at tertiary institutions, where a multidisciplinary team can handle the complex problems. Staging of these tumours implies accurate anatomic determination of the extent of disease, the histogenesis and grade of the tumours and the presence of regional or distant metastases. Arteriography, computed tomography and magnetic resonance imaging can accurately define the tumour before biopsy. The biopsy should be muscle-splitting to minimize contamination of additional compartments and should allow inclusion of the biopsy site at definitive surgical resection. It should be done at the institution where definitive management will be performed. Regional lymph-node involvement can be detected using magnetic resonance imaging or gallium scanning, whereas for distant metastases, specifically of lung, computed tomography is the method of choice. To date no one staging system for soft-tissue sarcomas has been universally accepted. A hybrid, encompassing the advantages of each system, is being formulated.
软组织肉瘤仅占所有恶性病变的1%。加拿大肉瘤研究小组鼓励在三级医疗机构对这些肿瘤进行研究和治疗，因为那里的多学科团队能够处理复杂问题。这些肿瘤的分期意味着要准确地从解剖学上确定疾病范围、肿瘤的组织发生和分级以及区域或远处转移的情况。动脉造影、计算机断层扫描和磁共振成像能够在活检前准确界定肿瘤。活检应采用肌肉劈开法，以尽量减少对其他组织间隙的污染，并应在确定性手术切除时将活检部位包括在内。活检应在将进行确定性治疗的机构进行。区域淋巴结受累情况可通过磁共振成像或镓扫描检测，而对于远处转移，尤其是肺部转移，计算机断层扫描是首选方法。迄今为止，尚无一种软组织肉瘤分期系统得到普遍认可。一种融合了各系统优点的混合分期系统正在制定中。
