Broggini M, Filardi G P, Volontè S, Bottà V, Cappelli A, Crespi E
Divisione B Medicina Generale, Ospedale Multizonale, Varese, Italy.
Clin Exp Rheumatol. 1988 Apr-Jun;6(2):141-3.
A 61-year-old woman, suffering from classic seropositive rheumatoid arthritis with rheumatoid nodule histologically documented, developed temporal arteritis. HLA-DR typing revealed the presence of DR3 and DR4 antigens. The findings from previous studies support the association of HLA-DR antigens, giant cell arteritis-polymyalgia rheumatica and rheumatoid arthritis, and suggest the participation of a common immunogenetic mechanism in their pathogenesis.
一名61岁女性,患有典型的血清阳性类风湿关节炎,组织学证实有类风湿结节,随后发生了颞动脉炎。HLA - DR分型显示存在DR3和DR4抗原。先前研究的结果支持HLA - DR抗原、巨细胞动脉炎 - 风湿性多肌痛和类风湿关节炎之间的关联,并提示共同的免疫遗传机制参与了它们的发病过程。