Seo Seung-Suk, Kim Chang-Wan, Lee Chang-Rack, Park Dae-Hyun, Kwon Yong-Uk, Jung Daewon, Kim Dong-Seon
Department of Orthopedic Surgery, Haeundae Bumin Hospital, 584, Haeundae-ro, Haeundae-gu, Busan 48094, Republic of Korea.
Department of Orthopedic Surgery, Inje University Busan Paik Hospital, 75, Bokji-ro, Busanjin-gu, Busan 47392, Republic of Korea.
Knee. 2020 Mar;27(2):444-450. doi: 10.1016/j.knee.2019.10.009. Epub 2019 Dec 2.
The aim of this study was to compare the functional outcomes and recurrence rate of infection between patients who underwent arthroscopic surgery and two-stage total knee arthroplasty (TKA) for infected arthritic knees.
A retrospective analysis was conducted on 52 patients (52 knees) with advanced knee joint arthritis who underwent arthroscopic surgery or two-stage TKA using articulating cement spacer (ACS) for knee joint infection between January 2009 and November 2013. Of the 52 patients (52 knees), 38 and 14 patients underwent arthroscopic surgery (AS group) and two-stage TKA using ACS (ACS-TKA group), respectively. Patient-reported outcomes (Knee Injury and Osteoarthritis Outcome Score (KOOS) and EuroQol-Visual Analog Scales (EQ-VAS)); range of motion; and recurrence rate of infection were evaluated.
Recurrence of infection was observed in 7/38 patients who underwent arthroscopic surgery, all of whom received two-stage TKA using ACS. Regarding the functional outcomes of the ACS-TKA group obtained before conversion to TKA and those of the AS group obtained six months after arthroscopic surgery, the former group had better outcomes for KOOS pain, KOOS activities of daily living, KOOS quality of life, and EQ-VAS. Regarding the functional outcomes of the ACS-TKA group obtained during the last follow-up and after conversion to TKA and those of the AS group who underwent TKA after arthroscopic surgery, no significant between-group differences were observed. The infection recurrence rate was higher in the AS than in the ACS-TKA group.
Considering infection control and functional outcomes, two-stage TKA using ACS can be an effective alternative treatment for patients with infected arthritic knees.
本研究旨在比较接受关节镜手术和两阶段全膝关节置换术(TKA)治疗感染性关节炎膝关节患者的功能结局和感染复发率。
对2009年1月至2013年11月期间接受关节镜手术或使用活动式骨水泥间隔器(ACS)进行两阶段TKA治疗膝关节感染的52例晚期膝关节关节炎患者(52膝)进行回顾性分析。在这52例患者(52膝)中,分别有38例和14例患者接受了关节镜手术(AS组)和使用ACS的两阶段TKA(ACS-TKA组)。评估患者报告的结局(膝关节损伤和骨关节炎结局评分(KOOS)和欧洲生活质量视觉模拟量表(EQ-VAS))、活动范围和感染复发率。
在接受关节镜手术的38例患者中有7例出现感染复发,所有这些患者均接受了使用ACS的两阶段TKA。关于转换为TKA之前获得的ACS-TKA组的功能结局以及关节镜手术后6个月获得的AS组的功能结局,前一组在KOOS疼痛、KOOS日常生活活动、KOOS生活质量和EQ-VAS方面有更好的结局。关于最后随访期间和转换为TKA后获得的ACS-TKA组的功能结局以及关节镜手术后接受TKA的AS组的功能结局,未观察到组间显著差异。AS组的感染复发率高于ACS-TKA组。
考虑到感染控制和功能结局,使用ACS的两阶段TKA可以成为感染性关节炎膝关节患者的一种有效替代治疗方法。