Le Flecher Arnaud, Viallet Nicolas, Hebmann Delphine, Chauveau Bertrand, Vacher Coponat Henri
Department of Nephrology - Transplantation, CHU de la Réunion Felix Guyon, Saint Denis, Réunion, France.
Department of Pathology, CHU Necker-Enfants Malades, Paris, France.
Clin Kidney J. 2019 Apr 23;12(6):801-802. doi: 10.1093/ckj/sfz044. eCollection 2019 Dec.
We report a 35-year-old man who suffered from recurrent macroscopic haematuria after intensive exercise. One episode was associated with bilateral loin (flank) pain and severe acute kidney injury. His kidney biopsy revealed an atypical anti-glomerular basement membrane (GBM) disease typified by bright linear GBM staining for monotypic immunoglobulin G but without a diffuse crescentic phenotype and no circulating anti-GBM antibody. Outcome was spontaneously favourable. The patient had no recurrence or urine abnormality without running. The original presentation emphasized that exercise could reveal an underlying glomerulopathy.
我们报告一名35岁男性，其在剧烈运动后反复出现肉眼血尿。其中一次发作伴有双侧腰痛及严重急性肾损伤。他的肾活检显示为非典型抗肾小球基底膜（GBM）病，其特征为单型免疫球蛋白G在肾小球基底膜呈明亮线性染色，但无弥漫性新月体表型且无循环抗GBM抗体。结果自发好转。该患者在不跑步时无复发及尿液异常。最初的表现强调运动可揭示潜在的肾小球病。
