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纤维肌痛患者的住院治疗:英格兰住院程序、费用和地域差异的队列水平观察性研究。

Hospitalization in fibromyalgia: a cohort-level observational study of in-patient procedures, costs and geographical variation in England.

机构信息

Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford.

Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

出版信息

Rheumatology (Oxford). 2020 Aug 1;59(8):2074-2084. doi: 10.1093/rheumatology/kez499.

Abstract

OBJECTIVES

Fibromyalgia is a complex, debilitating, multifactorial condition that can be difficult to manage. Recommended treatments are usually delivered in outpatient settings; evidence suggests that significant inpatient care occurs. We describe the scale and cost of inpatient care with a primary diagnostic code of fibromyalgia within the English National Health Service.

METHODS

We conducted a cohort-level observational study of all patients admitted to hospital due to a diagnosis of fibromyalgia, between 1 April 2014 and 31 March 2018 inclusive, in the National Health Service in England. We used data from Hospital Episode Statistics Admitted Patient Care to study: the age and sex of patients admitted, number and costs of admissions, length of stay, procedures undertaken, class and type of admission, and distribution of admissions across clinical commissioning groups.

RESULTS

A total of 24 295 inpatient admissions, costing £20 220 576, occurred during the 4-year study period. Most patients were women (89%) with peak age of admission of between 45 and 55 years. Most admissions were elective (92%). A number of invasive therapeutic procedures took place, including a continuous i.v. infusion (35%). There was marked geographical variation in the prevalence and cost of inpatient fibromyalgia care delivered across the country, even after accounting for clinical commissioning group size.

CONCLUSIONS

Many patients are admitted for treatment of their fibromyalgia and given invasive procedures for which there is weak evidence, with significant variation in practice and cost across the country. This highlights the need to identify areas of resource use that can be rationalized and diverted to provide more effective, evidence-based treatment.

摘要

目的

纤维肌痛是一种复杂、使人虚弱、多因素的疾病,可能难以治疗。推荐的治疗方法通常在门诊环境中进行;有证据表明,大量住院治疗是必要的。我们描述了英国国民保健系统中以纤维肌痛为主要诊断代码的住院患者的规模和费用。

方法

我们对 2014 年 4 月 1 日至 2018 年 3 月 31 日期间,因纤维肌痛诊断而住院的所有患者进行了队列水平的观察性研究,这些患者均在英格兰国民保健系统中接受治疗。我们使用医院入院统计数据中的入院患者护理数据,研究了以下内容:入院患者的年龄和性别、入院人数和费用、住院时间、进行的程序、入院的类别和类型,以及按临床委托组分布的入院情况。

结果

在 4 年的研究期间,共发生了 24295 例住院治疗,费用为 20220576 英镑。大多数患者为女性(89%),入院高峰期年龄在 45 至 55 岁之间。大多数入院为择期(92%)。进行了许多侵入性治疗程序,包括连续静脉输液(35%)。即使考虑到临床委托组的规模,全国范围内纤维肌痛住院治疗的流行程度和费用也存在明显的地域差异。

结论

许多患者因纤维肌痛接受治疗并接受侵入性治疗,而这些治疗的证据不足,全国各地的治疗方法和费用存在显著差异。这凸显了需要确定可以合理化和转移资源利用的领域,以提供更有效、基于证据的治疗方法。

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