Department of Cardiology, University Hospital of Rangueil, Toulouse, France.
Cardiac Imaging Center, Toulouse University Hospital, France.
Clin J Sport Med. 2021 Sep 1;31(5):414-422. doi: 10.1097/JSM.0000000000000769.
Participating in either competitive or leisure sports is restrictive after surgical mitral valve repair (MVR). In this study, we examine the impact of sports on outcomes after MVR.
Retrospective cohort study.
Patients aged 18 to 65 years who underwent a first-time MVR for primary mitral regurgitation (MR) in a tertiary care center.
One hundred twenty-one consecutive patients were included in the study. The exclusion criteria were as follows: other concomitant procedures, early perioperative death or repeat intervention, noncardiac death or endocarditis during follow-up, and general contraindications for normal physical activity.
Participation in sports was quantified by the number of hours per week during the past 6 months, classified according to the Mitchell classification and assessed with the International Physical Activity Questionnaire (IPAQ) short form.
The primary composite endpoint was MVR failure defined as MR grade ≥2 or mean transmitral gradient ≥8 mm Hg, signs and symptoms of heart failure, or late-onset postoperative AF (>3 months).
The mean age was 50 ± 11 years, and there were 85 (71%) men. The median follow-up was 34 months [interquartile range (IQR): 20-50]. Fifty-six (46%) patients participated in sports regularly (median of 3 h/wk; IQR: 2-5). Twenty (17%) patients reached the primary composite endpoint with no correlation with participation in sports (P = 0.537), IPAQ categories (P = 0.849), in any of the Mitchell classification subgroups and a high level of participation in sports ≥6 hours (P = 0.679).
Sports seem to be unrelated to the worst outcome after MVR.
在接受二尖瓣修复术（MVR）后，参与竞技或休闲运动可能会受到限制。本研究旨在探讨运动对 MVR 后结局的影响。
回顾性队列研究。
在一家三级护理中心接受首次 MVR 治疗原发性二尖瓣反流（MR）的 18 至 65 岁患者。
本研究共纳入 121 例连续患者。排除标准如下：其他伴随手术、围手术期早期死亡或再次干预、随访期间非心脏死亡或心内膜炎以及正常体力活动的一般禁忌。
通过过去 6 个月每周的小时数来量化运动参与度，根据 Mitchell 分类进行分类，并使用国际体力活动问卷（IPAQ）短表进行评估。
主要复合终点是 MVR 失败，定义为 MR 分级≥2 或平均跨瓣梯度≥8mmHg、心力衰竭的体征和症状或迟发性术后 AF（>3 个月）。
患者平均年龄为 50±11 岁，其中 85 例（71%）为男性。中位随访时间为 34 个月[四分位间距（IQR）：20-50]。56 例（46%）患者经常进行运动（中位数为每周 3 小时；IQR：2-5）。20 例（17%）患者达到主要复合终点，但与运动参与（P=0.537）、IPAQ 类别（P=0.849）、Mitchell 分类任何亚组以及高运动水平（≥6 小时）无关（P=0.679）。
运动似乎与 MVR 后最差结局无关。
