Safran Szilard Laszlo, Balmer Christian, Savoldelli Georges
Service d'anesthésiologie et de réanimation du CHVR, Hopital du Valais, Sion, Switzerland.
Department of Anaesthesiology, Clinical Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals, Geneva, Switzerland.
BMJ Case Rep. 2019 Dec 5;12(12):e230606. doi: 10.1136/bcr-2019-230606.
We describe the case of a 25-year-old parturient who presented sudden onset and short-lived severe headache caused by reversible cerebral vasoconstriction syndrome (RCVS) during an emergency caesarean section. The syndrome was triggered by phenylephrine administered intravenously to correct arterial hypotension following spinal anaesthesia. RCVS is a clinical and radiological syndrome attributed to transient disturbance in the control of cerebral arterial tone resulting in vasospasms. The syndrome can be precipitated by several triggers, including vasoactive drugs, often used during spinal anaesthesia, illicit drugs, pregnancy and postpartum state. Diagnosis and management can be challenging during pregnancy, peripartum or post partum, since many medications commonly used during these periods must be avoided to prevent triggering RCVS. The aim of this report is to raise the awareness, particularly for anaesthesiologists and obstetricians, of this rare and potentially serious syndrome. We discuss diagnosis, triggers, pathogenesis, clinical course and complications, as well as coordinated multidisciplinary management plans.
我们描述了一名25岁产妇的病例,她在急诊剖宫产期间因可逆性脑血管收缩综合征(RCVS)出现突发且短暂的严重头痛。该综合征由脊髓麻醉后静脉注射去氧肾上腺素纠正动脉低血压引发。RCVS是一种临床和放射学综合征,归因于脑动脉张力控制的短暂紊乱导致血管痉挛。该综合征可由多种诱因引发,包括脊髓麻醉期间常用的血管活性药物、非法药物、妊娠和产后状态。在妊娠、围产期或产后进行诊断和管理具有挑战性,因为必须避免这些时期常用的许多药物以防止引发RCVS。本报告的目的是提高对这种罕见且可能严重的综合征的认识,尤其是对麻醉医生和产科医生。我们讨论了诊断、诱因、发病机制、临床过程和并发症,以及协调的多学科管理计划。