Santos Ernestina, Zhang Yuening, Wilkins Alastair, Renowden Shelley, Scolding Neil
University of Bristol Institute of Clinical Neurosciences, Department of Neurology, Frenchay Hospital, Bristol, UK.
J Neurol Sci. 2009 Jan 15;276(1-2):189-92. doi: 10.1016/j.jns.2008.08.034. Epub 2008 Oct 2.
Reversible cerebral vasoconstriction syndromes are characterized by prolonged but reversible vasoconstriction of the cerebral arteries, presenting typically with thunderclap headache, with or without focal neurological signs or symptoms. They resemble primary central nervous system vasculitis but it is critical to differentiate these two entities. Here we draw attention to intracranial haemorrhage as an important and not uncommon clinical feature in reversible cerebral vasoconstriction syndrome. Four patients with reversible cerebral vasoconstriction syndrome, each presenting to a single unit with intracranial haemorrhage, are described. These descriptions of haemorrhage at presentation of RCVS extend the recognised clinical phenotype and so help to enhance recognition and diagnosis of this often unconsidered disorder.
可逆性脑血管收缩综合征的特征是脑动脉出现长时间但可逆的血管收缩，通常表现为霹雳样头痛，伴有或不伴有局灶性神经体征或症状。它们类似于原发性中枢神经系统血管炎，但区分这两种疾病至关重要。在此，我们提请注意颅内出血是可逆性脑血管收缩综合征的一个重要且并非不常见的临床特征。本文描述了4例可逆性脑血管收缩综合征患者，他们均因颅内出血就诊于同一科室。这些关于可逆性脑血管收缩综合征发病时出血情况的描述扩展了已被认可的临床表型，有助于提高对这种常被忽视疾病的认识和诊断。
