Wunderlich F, Brenner H H, Helwig M
Division of Parasitology, University of Duesseldorf, Federal Republic of Germany.
Infect Immun. 1988 Dec;56(12):3326-8. doi: 10.1128/iai.56.12.3326-3328.1988.
Plasmodium chabaudi-susceptible NMRI and B10.A mice were vaccinated with host cell plasma membranes isolated from P. chabaudi-infected erythrocytes. Most of the mice were protected from the lethal consequences of challenge with the homologous parasite, although protection was unassociated with a reduction in the course or peak of parasitemia. Vaccination also induced the production of antibodies against Pc90, which is the immunodominant protein expressed by parasites in host cell plasma membranes.