Freemont A J
University of Manchester Medical School, United Kingdom.
Int J Tissue React. 1988;10(2):85-8.
High endothelial venules (HEV) are vessels characteristic of lymph nodes specialized for promoting lymphocyte migration between blood and the nodal parenchyma. The studies outlined in this article constitute an overview of work done in my laboratory to investigate some functional aspects of HEV and a group of venules that develop in sites in lymphocyte accumulation in non-lymphoid tissues which resemble HEV in many ways and are therefore known as HEV-like vessels. This is followed by a hypothesis to explain the development of HEV-like vessels and its importance for lymphocyte traffic.
高内皮微静脉(HEV)是淋巴结特有的血管,专门促进淋巴细胞在血液和淋巴结实质之间迁移。本文概述的研究是对我实验室所做工作的综述,该工作旨在研究HEV以及一组在非淋巴组织中淋巴细胞聚集部位形成的微静脉的一些功能方面。这些微静脉在许多方面类似于HEV,因此被称为类HEV血管。接下来是一个假说,用以解释类HEV血管的形成及其对淋巴细胞运输的重要性。