Yardley Jane E
Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Canada.
Alberta Diabetes Institute, Edmonton, Canada.
Open Access J Sports Med. 2019 Dec 6;10:199-207. doi: 10.2147/OAJSM.S149257. eCollection 2019.
Fear of hypoglycemia is a common barrier to exercise and physical activity for individuals with type 1 diabetes. While some of the earliest studies in this area involved only one or two participants, the link between exercise, exogenous insulin, and hypoglycemia was already clear, with the only suggested management strategies being to decrease insulin dosage and/or consume carbohydrates before and after exercise. Over the past 50 years, a great deal of knowledge has been developed around the impact of different types and intensities of exercise on blood glucose levels in this population. Recent decades have also seen the development of technologies such as continuous glucose monitors, faster-acting insulins and commercially available insulin pumps to allow for the real-time observation of interstitial glucose levels, and more precise adjustments to insulin dosage before, during and after activity. As such, there are now evidence-based exercise and physical activity guidelines for individuals with type 1 diabetes. While the risk of hypoglycemia has not been completely eliminated, therapy recommendations have evolved considerably. This review discusses the evolution of the knowledge and the technology related to type 1 diabetes and exercise that have allowed this evolution to take place.
低血糖恐惧是1型糖尿病患者进行运动和体育活动的常见障碍。虽然该领域一些最早的研究仅涉及一两名参与者,但运动、外源性胰岛素和低血糖之间的联系已经很明确,当时唯一建议的管理策略是在运动前后减少胰岛素剂量和/或摄入碳水化合物。在过去50年里,围绕不同类型和强度的运动对该人群血糖水平的影响,人们已经积累了大量知识。近几十年来,连续血糖监测仪、速效胰岛素和商用胰岛素泵等技术也得到了发展,以便实时观察组织间液葡萄糖水平,并在活动前、活动期间和活动后更精确地调整胰岛素剂量。因此,现在有了针对1型糖尿病患者的循证运动和体育活动指南。虽然低血糖风险尚未完全消除,但治疗建议已经有了很大的演变。本综述讨论了与1型糖尿病和运动相关的知识和技术的演变,正是这些演变促成了上述变化。