Prince Mohammed bin Abdulaziz Hospital for National Guard, Madinah, Saudi Arabia.
Paediatric Endocrinology Department, Mafraq Hospital, Abu Dhabi, United Arab Emirates.
Diabetes Res Clin Pract. 2020 Jan;159:107975. doi: 10.1016/j.diabres.2019.107975. Epub 2019 Dec 10.
To ascertain the awareness and practice of neonatal diabetes mellitus (NDM) among paediatricians in Arab countries.
An online questionnaire was distributed to physicians associated with the Arab Society for Paediatric Endocrinology and Diabetes (ASPED).
We received 126 replies, from 16 countries. All except one classified the survey's case scenario as NDM and 94% agreed that NDM patients should have detailed assessment to identify extra-pancreatic features. Although 92% felt that genetic testing is necessary, only 72% requesting them routinely and 32% unaware of the availability of free genetic testing. Insulin is considered the initial therapy for 93% and 80% diluted insulin to deliver accurate doses. Basal-bolus regimen was preferred by 36% and similar percentage used insulin pump. The remaining 28% favour long acting insulin alone. Oral sulfonylureas would be tried empirically by 34% and 69% would do so if genetic testing is unavailable. Whilst 70% have no local NDM management guidelines, 41% are unaware of any international guidelines.
The ASPED surveyed clinicians have good awareness of NDM diagnosis with marked variation in their practice raising the need to establish management guideline for the condition. The survey highlights areas to focus on in developing consensus and educational activities.
了解阿拉伯国家儿科医生对新生儿糖尿病（NDM）的认知和实践情况。
向阿拉伯儿内分泌糖尿病学会（ASPED）的医生发放在线问卷。
我们收到了来自 16 个国家的 126 份回复。除了一位，所有人都将调查案例归类为 NDM，94%的人认为 NDM 患者应进行详细评估以确定胰腺外特征。尽管 92%的人认为基因检测是必要的，但只有 72%的人常规要求进行检测，32%的人不知道免费基因检测的可用性。93%的人认为胰岛素是初始治疗，80%的人稀释胰岛素以精确给药。36%的人首选基础-餐时胰岛素方案，相同比例的人使用胰岛素泵。其余 28%的人则倾向于单独使用长效胰岛素。34%的人会经验性地尝试口服磺脲类药物，如果基因检测不可用，69%的人会这样做。虽然 70%的人没有当地的 NDM 管理指南，但 41%的人不知道任何国际指南。
ASPED 调查的临床医生对 NDM 的诊断有很好的认识，但他们的实践存在明显差异，这需要为该疾病制定管理指南。该调查突出了在制定共识和教育活动方面需要关注的领域。
