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支架治疗开口部肺动脉分支狭窄:初始和中期结果以及为避免和最小化支架错位的技术考虑。

Stent treatment of ostial branch pulmonary artery stenosis: initial and medium-term outcomes and technical considerations to avoid and minimise stent malposition.

机构信息

Division of Pediatric Cardiology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Divison of Pediatric Cardiology, University of California Davis Children's Hospital, Sacramento, CA, USA.

出版信息

Cardiol Young. 2020 Feb;30(2):256-262. doi: 10.1017/S1047951119003032. Epub 2019 Dec 13.

Abstract

OBJECTIVE

Stenting of ostial pulmonary artery stenosis presents several unique challenges. These include difficulty in defining anatomy and need for precise stent placement in order to avoid missing the ostial stenosis or jailing either the contralateral branch pulmonary artery or the ipsilateral upper lobe branch.

DESIGN

A retrospective review of outcomes was conducted in 1.5 or 2-ventricle patients who underwent stent placement for ostial branch pulmonary artery stenosis. Specific catheterisation lab techniques were reviewed.

RESULTS

Forty-seven branch pulmonary arteries underwent stent placement for ostial stenosis in 43 patients. The median age and weight were 3.7 (0.3-18.1) years and 14.2 (5.6-70.0) kg, respectively. Three (2-8) angiographic projections were needed to profile the ostial stenosis. Open-cell stents were used in 23 and stents were modified in 5 cases. Following stent implantation, the minimum diameter improved from 3.6 (0.8-10.5) to 8.1 (4.2-16.5) mm (p < 0.001). The gradient improved from 21 (0-66) to 4 (0-27) mmHg (p < 0.001). Stent malposition occurred in eight (17%) of the stents placed. Five migrated distally causing suboptimal ostial coverage necessitating placement of a second stent in four. Three migrated proximally and partially jailed the contralateral pulmonary artery. Intentional jailing of the upper lobe branch occurred in four additional cases. At a follow-up of 2.4 (0.3-4.9) years, 15 stents underwent further dilation and 1 had a second stent placed within the exiting stent.

CONCLUSION

Ostial branch pulmonary artery stenosis may require additional angiography to accurately define the ostial stenosis. Treatment with stents is effective but carries high rates of stent malposition.

摘要

目的

肺动脉瓣狭窄的支架置入术存在一些独特的挑战。这些挑战包括难以确定解剖结构,以及需要精确放置支架,以避免错过瓣上狭窄或同时导致对侧肺动脉分支或同侧上叶分支受压。

设计

对 1.5 心室或 2 心室患者进行回顾性研究,这些患者因瓣上肺动脉分支狭窄而行支架置入术。回顾了特定的导管实验室技术。

结果

43 例患者的 47 支肺动脉瓣分支因瓣上狭窄而行支架置入术。患者的中位年龄和体重分别为 3.7(0.3-18.1)岁和 14.2(5.6-70.0)kg。需要 3(2-8)个血管造影投照体位来描绘瓣上狭窄。23 例使用开环支架,5 例支架需要修改。支架植入后,最小直径从 3.6(0.8-10.5)mm 增加到 8.1(4.2-16.5)mm(p<0.001)。梯度从 21(0-66)mmHg 降低到 4(0-27)mmHg(p<0.001)。8(17%)枚支架位置不当。5 枚支架向远端迁移,导致瓣上覆盖不理想,需要在 4 枚支架中放置第二枚支架。3 枚支架向近端迁移,部分压迫对侧肺动脉。4 例支架还导致了上叶分支的故意受压。在 2.4(0.3-4.9)年的随访中,15 枚支架进一步扩张,1 枚支架在原支架内再次放置。

结论

肺动脉瓣上分支狭窄可能需要额外的血管造影来准确地定义瓣上狭窄。支架治疗有效,但支架位置不当的发生率较高。

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