Revant Rehabilitation Centre, Breda, the Netherlands; Department of Neuropsychology and Psychopharmacology, Maastricht University, Maastricht, the Netherlands; Limburg Brain Injury Center, Maastricht, the Netherlands.
Revant Rehabilitation Centre, Breda, the Netherlands; Erasmus University Hospital/Sophia Children's Hospital, Department of Rehabilitation Medicine, Rotterdam, the Netherlands.
Eur J Paediatr Neurol. 2020 Mar;25:145-156. doi: 10.1016/j.ejpn.2019.11.008. Epub 2019 Dec 3.
This study aimed to identify predictors of long-term consequences for activities and participation in children and adolescents with mild traumatic brain injury (mTBI).
A multicentre prospective longitudinal cohort study was conducted. The primary outcome measure was activities and participation measured with the Child and Adolescent Scale of Participation - CASP and completed by children (N = 156) and caregivers (N = 231) six months post-mTBI. The CASP items were categorized into home, community, school, and environment. Predictors were categorized according to the International Classification of Functioning, Disability and Health for Children and Youth. Predictors included pre-injury personal- and environmental factors, injury-related factors, symptoms, and resumption of activities in the first two weeks after mTBI. Univariate and multivariate logistic regression analyses were used to determine the predictive value of these factors.
Results show that predictors differ across settings and perspectives (child or caregiver). Decreased activities and participation in children with mTBI can be predicted by adverse pre-injury behavioral functioning of the child (p < .000 - p = .038), adverse pre-injury family functioning (p = .001), lower parental SES (p = .038), more stress symptoms post-injury (p = .017 - p = .032), more post-concussive symptoms (p = .016 - p = .028) and less resumption of activities (p = .006 - p = .045).
Pre-injury factors, more symptoms post-injury and less resumption of activities should be considered when children are screened for unfavorable outcomes. Additional factors may add to the prediction, but injury-related factors do not. It is recommended that future research explores psychosocial factors, such as coping styles, emotion-regulation, personality traits, social support, and other comorbid problems of both children and caregivers.
本研究旨在确定轻度创伤性脑损伤(mTBI)患儿和青少年活动和参与的长期后果的预测因素。
进行了一项多中心前瞻性纵向队列研究。主要结局测量是使用儿童和青少年参与量表(Child and Adolescent Scale of Participation-CASP)测量的活动和参与度,该量表由 6 个月后 mTBI 的儿童(N=156)和照顾者(N=231)完成。CASP 项目分为家庭、社区、学校和环境。预测因素根据《儿童和青少年国际功能、残疾和健康分类》进行分类。预测因素包括受伤前的个人和环境因素、与损伤相关的因素、症状以及 mTBI 后前两周的活动恢复情况。使用单变量和多变量逻辑回归分析来确定这些因素的预测价值。
结果表明,预测因素在不同的环境和视角(儿童或照顾者)中有所不同。受伤前儿童的行为功能不良(p<0.000-p=0.038)、受伤前家庭功能不良(p=0.001)、父母 SES 较低(p=0.038)、受伤后应激症状较多(p=0.017-p=0.032)、脑震荡后症状较多(p=0.016-p=0.028)和活动恢复较少(p=0.006-p=0.045),可预测 mTBI 患儿的活动和参与度降低。
在对儿童进行不良结局筛查时,应考虑受伤前的因素、受伤后更多的症状和较少的活动恢复。其他因素可能会增加预测,但与损伤相关的因素则不会。建议未来的研究探索儿童和照顾者的社会心理因素,如应对方式、情绪调节、个性特征、社会支持和其他共病问题。