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口腔颌面部头颈部严重多间隙感染患者的致命并发症:一例报告

Fatal complications in a patient with severe multi-space infections in the oral and maxillofacial head and neck regions: A case report.

作者信息

Dai Tian-Guo, Ran Hong-Bing, Qiu Yin-Xiu, Xu Bo, Cheng Jin-Qiang, Liu Ying-Kai

机构信息

Department of Oral and Maxillofacial Surgery, Central Hospital of Panzhihua City, Panzhihua 617067, Sichuan Province, China.

Department of Otolaryngology Head and Neck Surgery, Central Hospital of Panzhihua City, Panzhihua 617067, Sichuan Province, China.

出版信息

World J Clin Cases. 2019 Dec 6;7(23):4150-4156. doi: 10.12998/wjcc.v7.i23.4150.

Abstract

BACKGROUND

Odontogenic infection is one of the common infectious diseases in oral and maxillofacial head and neck regions. Clinically, if early odontogenic infections such as acute periapical periodontitis, alveolar abscess, and pericoronitis of wisdom teeth are not treated timely, effectively and correctly, the infected tissue may spread up to the skull and brain, down to the thoracic cavity, abdominal cavity and other areas through the natural potential fascial space in the oral and maxillofacial head and neck. Severe multi-space infections are formed and can eventually lead to life-threatening complications (LTCs), such as intracranial infection, pleural effusion, empyema, sepsis and even death.

CASE SUMMARY

We report a rare case of death in a 41-year-old man with severe odontogenic multi-space infections in the oral and maxillofacial head and neck regions. One week before admission, due to pain in the right lower posterior teeth, the patient placed a cigarette butt dipped in the pesticide "Miehailin" into the "dental cavity" to relieve the pain. Within a week, the infection gradually spread bilaterally to the floor of the mouth, submandibular space, neck, chest, waist, back, temporal and other areas. The patient had difficulty breathing, swallowing and eating, and was transferred to our hospital as an emergency admission. Following admission, oral and maxillofacial surgeons immediately organized consultations with doctors in otolaryngology, thoracic surgery, general surgery, hematology, anesthesia and the intensive care unit to assist with treatment. The patient was treated with the highest level of antibiotics (vancomycin) and extensive abscess incision and drainage in the oral, maxillofacial, head and neck, chest and back regions. Unfortunately, the patient died of septic shock and multiple organ failure on the third day after admission.

CONCLUSION

Odontogenic infection can cause serious multi-space infections in the oral and maxillofacial head and neck regions, which can result in multiple LTCs. The management and treatment of LTCs such as multi-space infections should be multidisciplinary led by oral and maxillofacial surgeons.

摘要

背景

牙源性感染是口腔颌面部头颈部常见的感染性疾病之一。临床上,如果急性根尖周炎、牙槽脓肿、智齿冠周炎等早期牙源性感染未得到及时、有效、正确的治疗,感染组织可能通过口腔颌面部头颈部的天然潜在筋膜间隙向上蔓延至颅骨和脑部,向下蔓延至胸腔、腹腔等部位。形成严重的多间隙感染,最终可导致危及生命的并发症,如颅内感染、胸腔积液、脓胸、败血症甚至死亡。

病例摘要

我们报告一例41岁男性因口腔颌面部头颈部严重牙源性多间隙感染死亡的罕见病例。入院前一周,患者因右下后牙疼痛,将蘸有农药“灭害灵”的烟头放入“牙洞”以缓解疼痛。一周内,感染逐渐双侧蔓延至口底、颌下间隙、颈部、胸部、腰部、背部、颞部等区域。患者出现呼吸困难、吞咽及进食困难,作为急诊转入我院。入院后,口腔颌面外科医生立即组织与耳鼻喉科、胸外科、普通外科、血液科、麻醉科及重症监护室医生会诊以协助治疗。患者接受了最高级别的抗生素(万古霉素)治疗,并在口腔、颌面、头颈部、胸部及背部进行了广泛的脓肿切开引流。不幸地是,患者在入院后第三天死于感染性休克和多器官功能衰竭。

结论

牙源性感染可导致口腔颌面部头颈部严重的多间隙感染,进而引发多种危及生命的并发症。对于多间隙感染等危及生命的并发症的管理和治疗应以口腔颌面外科医生为主导进行多学科协作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b44c/6906581/10c69e8a6778/WJCC-7-4150-g001.jpg

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