Denicola Richard P, Coben Robert, Katz Leo, McCue Peter A
Department of Gastroenterology and Hepatology, Thomas Jefferson University Hospital, Philadelphia, PA.
Department of Pathology, Thomas Jefferson University Hospital, Philadelphia, PA.
ACG Case Rep J. 2019 Oct 15;6(10):e00238. doi: 10.14309/crj.0000000000000238. eCollection 2019 Oct.
Epstein-Barr virus (EBV) is a member of the herpesvirus family that is associated with various disease manifestations, including EBV-associated colitis. There are few case reports describing hemorrhage associated with EBV colitis. We report a 61-year-old woman with acute gastrointestinal bleeding due to EBV colitis after initiation of methylprednisolone and enoxaparin for spinal cord infarction. To our knowledge, there are only a few case reports of hemorrhagic EBV colitis. Perhaps we need to have a higher suspicion for EBV in cases of colitis associated with hemorrhage even in relatively immunocompetent patients.
爱泼斯坦-巴尔病毒(EBV)是疱疹病毒家族的一员,与多种疾病表现相关,包括EBV相关的结肠炎。描述EBV结肠炎相关出血的病例报告很少。我们报告了一名61岁女性,在因脊髓梗死开始使用甲泼尼龙和依诺肝素后,因EBV结肠炎出现急性胃肠道出血。据我们所知,出血性EBV结肠炎的病例报告仅有少数几例。也许即使在相对免疫功能正常的患者中,对于伴有出血的结肠炎病例,我们也需要对EBV有更高的怀疑。