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50赫兹电场对小鼠固定应激诱导的血浆糖皮质激素升高的抑制作用中的性别和年龄差异

Gender and Age Differences in the Suppressive Effect of a 50 Hz Electric Field on the Immobilization-Induced Increase of Plasma Glucocorticoid in Mice.

作者信息

Harakawa Shinji, Hori Takuya, Nedachi Takaki, Suzuki Hiroshi

机构信息

Bio-Self-Regulating Science Laboratory, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan.

Research and Development Department, Hakuju Institute for Health Science, Tokyo, Japan.

出版信息

Bioelectromagnetics. 2020 Feb;41(2):156-163. doi: 10.1002/bem.22238. Epub 2019 Dec 12.

DOI:10.1002/bem.22238
PMID:31833072
Abstract

We developed an experimental system to characterize the suppressive effect of extremely low-frequency (ELF) electric fields (EFs) on the stress response. We assessed differences in the EF effects by age and gender. Control, EF-alone, immobilization-alone, and co-treated groups were subjected to an EF (50 Hz, 10 kV/m). Co-treated mice were exposed to the EF for 60 min, with immobilization during the latter half. Our results indicate that the suppressive effects of ELF EFs on the stress response in immobilized mice occur regardless of gender or age. As stress plays an important role in the onset and progression of various diseases, these findings may have broad implications for understanding the efficacy of EFs in animal, and perhaps human, health. Bioelectromagnetics. 2020;41:156-163. © 2019 Bioelectromagnetics Society.

摘要

我们开发了一个实验系统,以表征极低频(ELF)电场(EFs)对应激反应的抑制作用。我们评估了不同年龄和性别的EF效应差异。对照组、单独施加EF组、单独固定组和联合处理组均暴露于EF(50Hz,10kV/m)。联合处理的小鼠暴露于EF 60分钟,后半段时间进行固定。我们的结果表明,ELF EFs对固定小鼠应激反应的抑制作用与性别或年龄无关。由于应激在各种疾病的发生和发展中起着重要作用,这些发现可能对理解EFs在动物乃至人类健康方面的功效具有广泛意义。《生物电磁学》。2020年;41:156 - 163。©2019生物电磁学协会。

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引用本文的文献

1
Suppression of Glucocorticoid Response in Stressed Mice Using 50 Hz Electric Field According to Immobilization Degree and Posture.根据固定程度和姿势,使用50Hz电场抑制应激小鼠的糖皮质激素反应。
Biology (Basel). 2022 Sep 9;11(9):1336. doi: 10.3390/biology11091336.
2
Stress-Reducing Effect of a 50 Hz Electric Field in Mice after Repeated Immobilizations, Electric Field Shields, and Polarization of the Electrodes.50赫兹电场对反复固定、电场屏蔽及电极极化后小鼠的应激减轻作用
Biology (Basel). 2022 Feb 17;11(2):323. doi: 10.3390/biology11020323.
3
Extremely low-frequency electric field suppresses not only induced stress response but also stress-related tissue damage in mice.
极低频电场不仅抑制了诱导的应激反应,还抑制了小鼠的应激相关组织损伤。
Sci Rep. 2020 Dec 7;10(1):20930. doi: 10.1038/s41598-020-76106-1.