哺乳动物红细胞葡萄糖磷酸化活性的比较研究。
Comparative studies on red blood cell glucose phosphorylating activities of mammals.
作者信息
Magnani M, Dachà M, Bossù M, Fornaini G
机构信息
Istituto di Chimica Biologica, Università degli Studi di Urbino, Italy.
出版信息
Comp Biochem Physiol B. 1978;60(3):323-7. doi: 10.1016/0305-0491(78)90108-6.
PMID:318347
Abstract
- ATP-D-hexose-6-phosphotransferase activity was measured in red blood cells of man, rabbit, pig and cow. Mean values ranged from 0.60 to 1.06 units/g haemoglobin and no significant difference was obtained with different glucose concentrations. 2. The characteristics of glucose phosphorylating activities in red blood cells of the species studied were similar. 3. Chromatography on DEAE column revealed two different glucose phosphorylating activities in red cells of man, rabbit and pig, and only one in cow red cells. 4. The first hexokinase activity is the predominant form and is saturated with low glucose concentrations; the second is noticeably marked at high glucose concentrations.
摘要
- 测定了人、兔、猪和牛红细胞中的ATP - D - 己糖 - 6 - 磷酸转移酶活性。平均值在0.60至1.06单位/克血红蛋白之间，不同葡萄糖浓度下未获得显著差异。2. 所研究物种的红细胞中葡萄糖磷酸化活性特征相似。3. DEAE柱色谱显示人、兔和猪的红细胞中有两种不同的葡萄糖磷酸化活性，而牛红细胞中只有一种。4. 第一种己糖激酶活性是主要形式，在低葡萄糖浓度下饱和；第二种在高葡萄糖浓度下明显显著。
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引用本文的文献
1
Molecular forms of red blood cell hexokinase.红细胞己糖激酶的分子形式。
Mol Cell Biochem. 1982 Dec 10;49(3):129-42. doi: 10.1007/BF00231174.
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