Wawrzynkiewicz Magdalena, Pastuszczak Maciej, Chlebicki Michał, Wojas-Pelc Anna
Department of Dermatology, Jagiellonian University Medical College, Krakow, Poland.
Faculty of Philosophy and Sociology, University of Warsaw, Warsaw, Poland.
Postepy Dermatol Alergol. 2019 Oct;36(5):581-588. doi: 10.5114/ada.2018.77500. Epub 2019 Aug 6.
Acral melanocytic nevi dermoscopic patterns have been well described in several populations. There have been no prospective studies assessing the prevalence, clinical characteristics and dermoscopic patterns of acral nevi in the Polish population.
To characterize the prevalence of acral nevi, frequency of dermoscopic patterns, relationships between acral nevi and patients' characteristics.
This was a prospective study conducted in the Dermatological Outpatient Clinic of the University Hospital in Krakow. Study inclusion criteria: presence of nevi on foot soles and/or palms, Caucasian race, Polish origin, and age ≥ 18 years.
Six hundred and twenty-four acral melanocytic lesions were observed in 287 patients, 174 (60.6%) women and 113 (39.4%) men, mean age 43.5 and 42.8 years, respectively. Four hundred and thirty-four (69.6%) lesions were present on soles, 190 (30.4%) on palms. No acral melanomas were detected. The following dermoscopic patterns were observed: parallel furrow 262 (42%), lattice-like 106 (17%), fibrillar 66 (11%) and other 190 (30%). Patients with acral nevi on the soles or both on the palms and soles had a higher number of atypical nevi on the body ( = 0.011) and a much higher total body nevi count ( = 0.043), when compared to those with acral nevi only on the palms.
The study revealed a higher prevalence of acral nevi in the analysed population. A higher number of acral nevi was associated with a higher number of atypical nevi and higher total body nevi count, the risk factors for melanoma. Because of that it is possible to note that a higher number of acral nevi should increase diagnostic alertness.
肢端黑素细胞痣的皮肤镜表现已在多个群体中得到充分描述。目前尚无前瞻性研究评估波兰人群中肢端痣的患病率、临床特征和皮肤镜表现。
描述肢端痣的患病率、皮肤镜表现的频率以及肢端痣与患者特征之间的关系。
这是一项在克拉科夫大学医院皮肤科门诊进行的前瞻性研究。研究纳入标准：足底和/或手掌有痣、白种人、波兰裔且年龄≥18岁。
在287例患者中观察到624个肢端黑素细胞病变，其中女性174例（60.6%），男性113例（39.4%），平均年龄分别为43.5岁和42.8岁。434个（69.6%）病变位于足底，190个（30.4%）位于手掌。未检测到肢端黑色素瘤。观察到以下皮肤镜表现：平行沟状262个（42%）、网格状106个（17%）、纤维状66个（11%）和其他190个（30%）。与仅手掌有肢端痣的患者相比，足底或手掌和足底均有肢端痣的患者身体上非典型痣的数量更多（P = 0.011），全身痣总数更高（P = 0.043）。
该研究显示在分析的人群中肢端痣的患病率较高。肢端痣数量较多与非典型痣数量较多以及全身痣总数较高相关，而这些都是黑色素瘤的危险因素。因此，可以注意到肢端痣数量较多应提高诊断警惕性。
