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Outcome of in vitro fertilization cycles with preimplantation genetic testing for aneuploidies: let's be honest with one another.

作者信息

Paulson Richard J

机构信息

Department of Obstetrics & Gynecology, Keck School of Medicine, University of Southern California, California.

出版信息

Fertil Steril. 2019 Dec;112(6):1013-1014. doi: 10.1016/j.fertnstert.2019.11.002.

DOI:10.1016/j.fertnstert.2019.11.002
PMID:31843071
Abstract
摘要

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Outcome of in vitro fertilization cycles with preimplantation genetic testing for aneuploidies: let's be honest with one another.进行非整倍体植入前基因检测的体外受精周期的结果：让我们坦诚相待。
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Abnormally fertilized oocytes can result in healthy live births: improved genetic technologies for preimplantation genetic testing can be used to rescue viable embryos in in vitro fertilization cycles.异常受精的卵母细胞可导致健康的活产：用于胚胎植入前基因检测的改进基因技术可用于在体外受精周期中挽救有活力的胚胎。
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Next generation sequencing for preimplantation genetic screening improves pregnancy outcomes compared with array comparative genomic hybridization in single thawed euploid embryo transfer cycles.与单枚解冻整倍体胚胎移植周期中的阵列比较基因组杂交相比，胚胎植入前遗传学筛查的新一代测序可改善妊娠结局。
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Why do euploid embryos miscarry? A case-control study comparing the rate of aneuploidy within presumed euploid embryos that resulted in miscarriage or live birth using next-generation sequencing.整倍体胚胎为何会流产？一项病例对照研究，使用下一代测序技术比较导致流产或活产的假定整倍体胚胎中的非整倍体率。
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Preimplantation Genetic Testing for Aneuploidy in Recurrent Pregnancy Loss: A Fertility Success Story.反复妊娠丢失中染色体非整倍体的植入前基因检测：一个生育成功的故事。
Cureus. 2025 May 14;17(5):e84084. doi: 10.7759/cureus.84084. eCollection 2025 May.
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PGT-A: what's it for, what's wrong?胚胎植入前非整倍体基因检测（PGT-A）：它用于什么，存在什么问题？
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An additive opinion to the committee opinion of ASRM and SART on the use of preimplantation genetic testing for aneuploidy (PGT-A).
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J Assist Reprod Genet. 2025 Jan;42(1):71-80. doi: 10.1007/s10815-024-03318-z. Epub 2024 Dec 18.
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F S Rep. 2023 Nov 8;4(4):329-330. doi: 10.1016/j.xfre.2023.11.002. eCollection 2023 Dec.
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Current Applications and Controversies in Preimplantation Genetic Testing for Aneuploidies (PGT-A) in In Vitro Fertilization.体外受精中胚胎植入前遗传学检测非整倍体（PGT-A）的当前应用和争议。
Reprod Sci. 2024 Jan;31(1):66-80. doi: 10.1007/s43032-023-01301-0. Epub 2023 Jul 29.
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PGT-A is associated with reduced cumulative live birth rate in first reported IVF stimulation cycles age ≤ 40: an analysis of 133,494 autologous cycles reported to SART CORS.PGT-A 与 ≤ 40 岁首次报告的 IVF 刺激周期中累积活产率降低相关：对向 SART CORS 报告的 133494 个自体周期的分析。
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