Kobayashi Arika, Matsunuma Ryoichi, Yamaguchi Kei, Hayami Ryosuke, Tsuneizumi Michiko, Nakagami Kazuhiko
Department of Breast Surgery, Shizuoka Prefectural Hospital Organization, Shizuoka General Hospital, Shizuoka 420-8527, Japan.
Oxf Med Case Reports. 2019 Dec 9;2019(11):473-475. doi: 10.1093/omcr/omz114. eCollection 2019 Nov.
Neoadjuvant chemotherapy is now a widely accepted treatment modality for operable breast cancer and therefore fertility preservation is an important component of care for young patients with breast cancer. It is critical that oocyte retrieval is completed without delays in the initiation of neoadjuvant chemotherapy. Here we report the case of a 34-year-old woman who was diagnosed with Stage IIA triple-negative breast cancer and underwent ovarian stimulation for fertility preservation prior to the initiation of neoadjuvant chemotherapy. Oocytes were retrieved and fertilization was conducted before neoadjuvant chemotherapy was started. Upon completion of neoadjuvant chemotherapy, the patient underwent breast surgery. Subsequently, a pathological complete response was achieved. She received a frozen embryo transfer 10 months after breast surgery. The patient became pregnant and delivered a healthy baby.
新辅助化疗目前是可手术乳腺癌广泛接受的一种治疗方式，因此，生育力保护是年轻乳腺癌患者护理的一个重要组成部分。在新辅助化疗开始时及时完成卵母细胞采集至关重要。在此，我们报告一例34岁女性，她被诊断为IIA期三阴性乳腺癌，并在新辅助化疗开始前接受了卵巢刺激以保护生育力。在新辅助化疗开始前采集了卵母细胞并进行了受精。新辅助化疗完成后，患者接受了乳房手术。随后，实现了病理完全缓解。乳房手术后10个月，她接受了冻融胚胎移植。患者成功怀孕并诞下一名健康婴儿。
