皮肤黑色素瘤手术的新趋势
New Trends in Cutaneous Melanoma Surgery.
作者信息
Scala Jacopo, Vojvodic Aleksandra, Vojvodic Petar, Vlaskovic-Jovicevic Tatjana, Peric-Hajzler Zorica, Matovic Dusica, Dimitrijevic Sanja, Vojvodic Jovana, Sijan Goran, Stepic Nenad, Wollina Uwe, Tirant Michael, Thuong Nguyen Van, Fioranelli Massimo, Lotti Torello
机构信息
University G. Marconi, Rome, Italy.
Department of Dermatology and Venereology, Military Medical Academy, Belgrade, Serbia.
出版信息
Open Access Maced J Med Sci. 2019 Sep 14;7(18):3090-3092. doi: 10.3889/oamjms.2019.828. eCollection 2019 Sep 30.
Abstract
The main surgical treatment for melanoma consists in wide surgical excision of the primary lesion and the sentinel node but in recent times management of melanoma is rapidly evolving with the introduction of new systemic therapies, like BRAF inhibitors, MEK inhibitors and antibodies anti-PD-1 that show good results in controlling even advanced stages of the disease. This review aims to present data for the optimal surgical management of patients with malignant melanoma.
摘要
黑色素瘤的主要手术治疗方法包括对原发灶和前哨淋巴结进行广泛手术切除，但近年来，随着新型全身治疗方法的引入，黑色素瘤的治疗正在迅速发展，如BRAF抑制剂、MEK抑制剂和抗PD-1抗体，这些药物在控制疾病的晚期阶段也显示出良好的效果。本综述旨在提供有关恶性黑色素瘤患者最佳手术治疗的数据。
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