Departments of Orthopaedic Surgery (N.J.O., P.J.A., and C.M.) and Psychiatry (D.W.H.), Carilion Clinic, Roanoke, Virginia.
Virginia Tech Carilion School of Medicine, Roanoke, Virginia.
J Bone Joint Surg Am. 2020 Feb 19;102(4):332-339. doi: 10.2106/JBJS.19.00241.
The opioid crisis is a well-known public health issue. The risk of new long-term opioid prescription-filling behavior has been investigated after certain spinal procedures and total knee and hip arthroplasty. However, this has not been examined after many other common orthopaedic procedures. The purpose of this study was to determine the rates of long-term opioid prescription-filling behavior after common orthopaedic surgical procedures in patients who were not taking opioids preoperatively.
This study utilized the Virginia All-Payer Claims Database (APCD), an insurance claims database with data from 3.7 to 4 million patients per year. Patients who underwent orthopaedic procedures and who had not filled an opioid prescription in the time period from 2 weeks to 1 year preceding the surgical procedure were selected for evaluation in our study. The percentage of these patients who then filled at least 10 prescriptions or a 120-day supply of opioids in the time period from 90 to 455 days following the surgical procedure was calculated for the 50 most commonly billed orthopaedic surgical procedures.
The rate of long-term opioid prescription-filling behavior in patients who were not taking opioids preoperatively for the 50 most common orthopaedic procedures was 5.3% (95% confidence interval, 5.1% to 5.5%). The highest rates were observed after spinal procedures. The lowest rates were seen after anterior cruciate ligament (ACL) reconstruction. Revision surgical procedures were found to have a significantly higher rate than primary procedures (p < 0.05). The rate was also related to increasing case complexity.
New long-term opioid prescription-filling behavior is common after orthopaedic surgical procedures in patients who were not taking opioids preoperatively. Risk factors include spine surgery, revision surgery, and cases with increased complexity. Orthopaedic surgeons need to be aware of this risk.
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
阿片类药物危机是一个众所周知的公共卫生问题。已经研究了某些脊柱手术后、全膝关节和髋关节置换术后新的长期阿片类药物处方填药行为的风险。然而,这在许多其他常见的骨科手术后尚未进行检查。本研究的目的是确定在术前未服用阿片类药物的患者中,常见骨科手术后长期阿片类药物处方填药行为的发生率。
本研究利用了弗吉尼亚州所有支付者索赔数据库(APCD),这是一个包含每年 370 万至 400 万患者数据的保险索赔数据库。选择接受骨科手术且在手术前 2 周到 1 年内未开具阿片类药物处方的患者进行本研究评估。计算了这些患者中在手术后 90 至 455 天内至少开具 10 份处方或 120 天供应量阿片类药物的比例,涵盖了 50 种最常见的计费骨科手术。
在 50 种最常见的骨科手术中,术前未服用阿片类药物的患者长期阿片类药物处方填药行为的发生率为 5.3%(95%置信区间,5.1%至 5.5%)。在脊柱手术后观察到最高的发生率。在前交叉韧带(ACL)重建后观察到最低的发生率。翻修手术被发现比初次手术具有显著更高的发生率(p < 0.05)。该比率还与病例复杂性的增加有关。
在术前未服用阿片类药物的患者中,骨科手术后新的长期阿片类药物处方填药行为很常见。风险因素包括脊柱手术、翻修手术和病例复杂性增加。骨科医生需要意识到这一风险。
预后 III 级。有关完整的证据水平说明,请参见作者说明。