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医院环境中记录药品不良反应的电子记录质量:差异识别与信息完整性

Quality of electronic records documenting adverse drug reactions within a hospital setting: identification of discrepancies and information completeness.

作者信息

Braund Rhiannon, Lawrence Courtney K, Baum Lindsay, Kessler Brittany, Vassart Madison, Coulter Carolyn

机构信息

Associate Professor at the New Zealand Pharmacovigilance Centre, University of Otago, Dunedin.

BSc in Pharmacy Candidate, University of Manitoba, College of Pharmacy, Winnipeg, Manitoba, Canada.

出版信息

N Z Med J. 2019 Jan 18;132(1488):28-37.

Abstract

AIM

Incomplete and incorrect documentation of adverse drug reactions (ADRs) can restrict prescribing choices resulting in suboptimal pharmaceutical care. This study aimed to examine the quality of information held within electronic systems in a hospital setting, to determine the preciseness of ADR documentation, and identify discrepancies where multiple electronic systems are utilised.

METHOD

Over a four-week period, consecutive patients admitted to the general medical ward at the study hospital had their electronic profiles reviewed. Patient demographic information (de-identified), ADR history and discrepancies between information sources (as recorded in all electronic systems utilised at initial prescribing) were recorded and analysed.

RESULTS

Over the four-week period, 332 patient profiles were reviewed, and over 1,200 alerts were identified and analysed (including duplicates of ADR reactions). Of these patients, 151 (45.5%) had at least one documented allergy or intolerance which generated 585 reactions, relating to 526 unique events. A further 151 (45.5%) were classified as having no known (drug) allergies or intolerances; however, 20 (15%) of these patients did have at least one allergy documented in at least one other electronic system. The remaining 30 (9%) patients were classified as having an unknown allergy status and of those nine had allergies documented in at least one other electronic system. Further, most systems contained information duplication, which had not been addressed during the admission process.

CONCLUSION

ADR information was both imprecise and inaccurate, as multiple discrepancies between ADR information recorded in different electronic patient management systems were found to exist. Information sharing between systems needs to be prioritised in order to allow full, accurate and complete ADR information to be collected, stored and utilised; both to reduce current inadequacies and to allow optimal pharmaceutical care.

摘要

目的

药物不良反应(ADR)记录不完整和不正确会限制处方选择,导致药物治疗效果欠佳。本研究旨在检查医院环境中电子系统所保存信息的质量,确定ADR记录的准确性,并识别在使用多个电子系统时存在的差异。

方法

在为期四周的时间里,对研究医院普通内科病房收治的连续患者的电子病历进行审查。记录并分析患者人口统计学信息(去识别化)、ADR病史以及信息来源之间的差异(如初始开处方时使用的所有电子系统中所记录的)。

结果

在四周期间,审查了332份患者病历,识别并分析了1200多条警报(包括ADR反应的重复记录)。在这些患者中,151名(45.5%)至少有一项记录在案的过敏或不耐受情况,产生了585次反应,涉及526个独特事件。另外151名(45.5%)被归类为无已知(药物)过敏或不耐受情况;然而,这些患者中有20名(15%)在至少一个其他电子系统中至少有一项过敏记录。其余30名(9%)患者被归类为过敏状态不明,其中9名在至少一个其他电子系统中有过敏记录。此外,大多数系统都存在信息重复的情况,在入院过程中未得到处理。

结论

由于发现不同电子患者管理系统中记录的ADR信息之间存在多重差异,ADR信息既不精确也不准确。需要优先考虑系统之间的信息共享,以便能够收集、存储和利用完整、准确和全面的ADR信息;既减少当前的不足,又实现最佳的药物治疗。

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