回到未来：T 细胞耗竭过程中的效应器命运。
Back to the Future: Effector Fate during T Cell Exhaustion.
机构信息
Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München (TUM), Munich, Germany.
Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München (TUM), Munich, Germany; German Center for Infection Research (DZIF), Partner site Munich, Germany.
出版信息
Immunity. 2019 Dec 17;51(6):970-972. doi: 10.1016/j.immuni.2019.11.007.
Exhausted CD8 T cells adopt a functionally attenuated state but still confer a certain degree of pathogen control. Chen et al. (2019), Hudson et al. (2019), and Zander et al. (2019) assign the lasting maintenance of this restrained pathogen control to an equilibrium of effector-like, transitory, terminal, and memory-like exhausted T cells.
耗尽的 CD8 T 细胞会采用一种功能减弱的状态，但仍能在一定程度上控制病原体。Chen 等人（2019 年）、Hudson 等人（2019 年）和 Zander 等人（2019 年）将这种受限的病原体控制的持续维持归因于效应样、短暂、终末和记忆样耗尽 T 细胞之间的平衡。
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