Graduate School of Tianjin Medical University, Tianjin, China.
Department of Urology, Characteristic Medical Center of Chinese People's Armed Police Forces, Tianjin, China,
Urol Int. 2020;104(5-6):361-366. doi: 10.1159/000503331. Epub 2019 Dec 18.
To investigate and compare the influence of two numerical detrusor contractility parameters, the bladder contractility index (BCI) and the maximum Watts factor (WFmax), on transurethral resection of the prostate (TURP) outcome.
A retrospective study was conducted on 236 patients who had undergone urodynamic assessment preoperatively and TURP for benign prostatic obstruction. They were evaluated by International Prostate Symptom Score (IPSS) and uroflowmetry preoperatively and 3 months postoperatively. Related criteria were established to determine the overall efficacy of TURP. Logistic regression analysis and receiver operating characteristic curves were made to investigate the influence of the BCI and WFmax on TURP efficacy.
Among the 236 patients, 195 treatments were effective and 41 ineffective. Multivariate analysis showed that both the BCI (OR 1.038) and the WFmax (OR 1.291) could influence TURP efficacy. For predicting TURP efficacy, the optimal cut-off values of the BCI and WFmax were 98.7 and 10.27 W/m2, respectively. The AUC, sensitivity and specificity of the BCI were 0.722, 78.5% and 61.0%; those of the WFmax were 0.761, 73.9% and 73.2%, with no significant difference (p > 0.05).
To some extent, the BCI and the WFmax can predict TURP efficacy equally well. A discrimination level of 10.27 W/m2 may be a threshold value for detrusor underactivity (DU); as regards the BCI, the current threshold value is appropriate to diagnose DU.
探讨和比较两种数值逼尿肌收缩力参数,即膀胱收缩力指数(BCI)和最大瓦特因子(WFmax)对经尿道前列腺切除术(TURP)效果的影响。
对 236 例因良性前列腺梗阻接受尿动力学评估和 TURP 的患者进行回顾性研究。术前和术后 3 个月分别采用国际前列腺症状评分(IPSS)和尿流率进行评估。确定了总体 TURP 疗效的相关标准。采用逻辑回归分析和受试者工作特征曲线(ROC)分析 BCI 和 WFmax 对 TURP 疗效的影响。
在 236 例患者中,195 例治疗有效,41 例无效。多因素分析显示,BCI(OR 1.038)和 WFmax(OR 1.291)均能影响 TURP 疗效。预测 TURP 疗效的 BCI 和 WFmax 的最佳截断值分别为 98.7 和 10.27 W/m2。BCI 的 AUC、敏感性和特异性分别为 0.722、78.5%和 61.0%;WFmax 的 AUC、敏感性和特异性分别为 0.761、73.9%和 73.2%,差异无统计学意义(p>0.05)。
BCI 和 WFmax 在一定程度上可以同样准确地预测 TURP 疗效。10.27 W/m2 可能是逼尿肌活动不足(DU)的分界值;就 BCI 而言,目前的分界值适用于诊断 DU。