Wu Shuangqing, Yu Xiaoyu, Dai Qi, Fu Yana, Lin Xiaolei
Department of Ophthalmology, Zhejiang Provincial Integrated Chinese and Western Medicine Hospital, Hangzhou.
Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Medicine (Baltimore). 2019 Dec;98(50):e18417. doi: 10.1097/MD.0000000000018417.
Spontaneous absorption of lenses or cataracts is rare. However, lens capsule attachment to the endothelium combined with corneal decompensation can still occur.
An 81-year-old male presented with left eye pain and bulbar conjunctival injection for 6 months. Diffuse corneal edema and inferior bullous lesions were observed by slit-lamp microscopy. Following examination with swept-source optical coherence tomography, we could clearly identify a membrane structure adherent to the corneal endothelium, as well as a lens not in situ. In vivo confocal microscopy found decreased corneal endothelial density of 745 ± 46 cells per mm in the left eye.
Lens dislocation and spontaneous absorption, combined with corneal decompensation were diagnosed.
Surgical removal of the membrane structure combined with anterior vitrectomy was performed.
The patient's symptoms were partly relieved. However, the corneal endothelial decompensation could not be entirely reversed. In vivo confocal microscopy verified that corneal endothelium was in situ and the density was not significantly changed in the left eye.
This case study reports a rare dislocation and spontaneous absorption of lens without any trauma or subsequent surgery. Moreover, it demonstrates corneal endothelial decompensation due to the lens capsule adhering to the corneal endothelium. Timely intervention is required to remove the dislocated lens and prevent complications.
晶状体或白内障的自发吸收很少见。然而,晶状体囊膜与内皮细胞附着并伴有角膜失代偿的情况仍可能发生。
一名81岁男性因左眼疼痛和球结膜充血6个月前来就诊。裂隙灯显微镜检查发现弥漫性角膜水肿和下方大疱性病变。经扫频光学相干断层扫描检查后,我们能够清晰地识别出附着于角膜内皮的膜结构以及不在原位的晶状体。活体共聚焦显微镜检查发现左眼角膜内皮密度降至每平方毫米745±46个细胞。
诊断为晶状体脱位并自发吸收,同时伴有角膜失代偿。
进行了膜结构手术切除并联合前部玻璃体切除术。
患者症状部分缓解。然而,角膜内皮失代偿未能完全逆转。活体共聚焦显微镜检查证实左眼角膜内皮在位且密度无明显变化。
本病例报告了一例罕见的无任何外伤或后续手术史的晶状体脱位并自发吸收的情况。此外,还证明了由于晶状体囊膜附着于角膜内皮导致的角膜内皮失代偿。需要及时干预以取出脱位的晶状体并预防并发症。