Lucertini Marco, Lancia Stefania, Sanjust Filippo, Guadagno Anton G, Lucertini Lorenzo, Sisto Renata
Aerosp Med Hum Perform. 2020 Jan 1;91(1):32-36. doi: 10.3357/AMHP.5421.2020.
The aim of this study was pure tone audiometry (PTA) evaluation in normal individuals exposed to hypobaric hypoxia, taking into account the influence of air rarefaction on sound transmission via a standard earphone. The study was conducted in a hypobaric chamber using a standard audiometer and a TDH-39P earphone whose performance at altitudes was analyzed in a previous research. Eight male volunteers underwent PTA testing at ground level and at 15,000 ft under normoxia (via an oxygen mask) and after 20 min of hypoxia. Auditory threshold at 500, 1000, 2000, and 4000 Hz was recorded from the right ear while monitoring arterial oxygen saturation (So₂). The PTA data obtained at high altitude were corrected according to a specific recalibration table. During hypoxia, a significant threshold shift was observed only at 4000 Hz, with respect to ground level recording, for the sole not-corrected data. At the same frequency a significant threshold shift was also observed between the ground level recording and normoxia at 15,000 ft, confirming the presence of a hypobaric effect not related to hypoxia. After the recalibration procedure, this hearing impairment was not significant. No correlation with So₂ levels was observed. The mild and not significant presence of high altitude-induced PTA derangements in healthy normal individuals was documented, although a stimulus recalibration was needed for a correct interpretation of our data.
本研究的目的是对暴露于低压低氧环境的正常个体进行纯音听力测定(PTA)评估,同时考虑空气稀薄对通过标准耳机传播声音的影响。该研究在低压舱中进行,使用标准听力计和TDH - 39P耳机,其在不同海拔高度的性能已在先前研究中进行了分析。八名男性志愿者在海平面、常氧状态下(通过氧气面罩)15000英尺高度以及缺氧20分钟后分别接受了PTA测试。在监测动脉血氧饱和度(So₂)的同时,记录右耳在500、1000、2000和4000赫兹时的听觉阈值。在高海拔地区获得的PTA数据根据特定的重新校准表进行了校正。在缺氧期间,仅对于未校正的数据,相对于海平面记录,在4000赫兹处观察到显著的阈值变化。在相同频率下,在海平面记录与15000英尺常氧状态之间也观察到显著的阈值变化,证实存在与缺氧无关的低压效应。经过重新校准程序后,这种听力损伤并不显著。未观察到与So₂水平的相关性。尽管需要对刺激进行重新校准以正确解释我们的数据,但已记录了健康正常个体中存在轻度且不显著的高海拔诱导的PTA紊乱情况。