患有2i型肢带型肌营养不良和扩张型心肌病女性的产科管理
Obstetric management of a woman with limb-girdle muscular dystrophy type 2i and dilated cardiomyopathy.
作者信息
von Guionneau Alexandra, Burford Charlotte, Stone Sophia
机构信息
Faculty of Life Sciences and Medicine, King's College London, London, UK.
Department of Obstetrics and Gynaecology, Western Sussex Hospitals NHS Foundation Trust, West Sussex, UK.
出版信息
Obstet Med. 2019 Dec;12(4):199-201. doi: 10.1177/1753495X18814622. Epub 2018 Dec 11.
Abstract
Limb-girdle muscular dystrophy describes a clinical phenotype with progressive weakness and atrophy of the muscles of the shoulders and hips. One of the more common types, limb-girdle muscular dystrophy type 2i, is associated with impaired cardiac function and restrictive lung disease, typically disproportionate to muscular disease. This condition presents a number of complex challenges in pregnancy and there are few case reports of its successful management. Here we discuss the course of the first pregnancy of a 20-year-old woman with limb-girdle muscular dystrophy type 2i.
摘要
肢带型肌营养不良描述了一种临床表型，其特征为肩部和髋部肌肉进行性无力和萎缩。较为常见的类型之一，即2i型肢带型肌营养不良，与心脏功能受损和限制性肺病有关，通常与肌肉疾病不成比例。这种情况在妊娠期间带来了许多复杂的挑战，成功管理的病例报告很少。在此，我们讨论一名患有2i型肢带型肌营养不良的20岁女性的首次妊娠过程。
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