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前哨淋巴结中同时存在结节病性肉芽肿和黑色素瘤微转移——病例报告

Concurrent sarcoidal granulomas and melanoma micrometastasis in a sentinel node - a case report.

作者信息

Trøstrup Hannah, Behrendt Nille, Mogensen Anne Mellon, Saltvig Iselin, Bandier Phillipe Claus, Hesselfeldt Jørgen, Løvenwald Jette B

机构信息

Department of Plastic Surgery and Breast Surgery, Zealand University Hospital, Roskilde, Denmark.

Department of Pathology, Zealand University Hospital, Roskilde, Denmark.

出版信息

Case Reports Plast Surg Hand Surg. 2019 Dec 5;6(1):105-108. doi: 10.1080/23320885.2019.1694412. eCollection 2019.

DOI:10.1080/23320885.2019.1694412
PMID:31853463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6913662/
Abstract

Incidental findings of non-caseating granulomas and metastasis in sentinel lymph nodes are rare but cause clinical challenges. We report a case of coinciding unexpected asymptomatic lymphoid sarcoidosis and a micrometastasis in a sentinel node of a patient, who was newly diagnosed with 2.0 mm thick melanoma on the left calf.

摘要

前哨淋巴结中出现非干酪样肉芽肿和转移的偶然发现很罕见，但会引发临床挑战。我们报告了一例患者，其新诊断为左小腿2.0毫米厚的黑色素瘤，在前哨淋巴结中同时出现了意外的无症状淋巴样结节病和微转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbe/6913662/5e23341e9016/ICRP_A_1694412_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbe/6913662/e64dbef74c39/ICRP_A_1694412_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbe/6913662/656710148221/ICRP_A_1694412_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbe/6913662/5e23341e9016/ICRP_A_1694412_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbe/6913662/e64dbef74c39/ICRP_A_1694412_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbe/6913662/656710148221/ICRP_A_1694412_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbe/6913662/5e23341e9016/ICRP_A_1694412_F0003_C.jpg

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本文引用的文献

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Sarcoid-like reactions in patients receiving modern melanoma treatment.接受现代黑色素瘤治疗的患者中的结节病样反应。
Melanoma Res. 2018 Jun;28(3):230-236. doi: 10.1097/CMR.0000000000000437.
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Coexistence of sarcoidosis and metastatic lesions: A diagnostic and therapeutic dilemma.结节病与转移性病变并存：诊断与治疗的困境
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Oncoimmunology. 2014 Aug 3;3(8):e954506. doi: 10.4161/21624011.2014.954506. eCollection 2014.
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Subcutaneous sarcoidosis in a melanoma scar.黑色素瘤瘢痕中的皮下结节病。
Cutis. 2011 May;87(5):234-6.
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Concurrent sarcoidosis and melanoma: coexistence more than by chance?结节病与黑色素瘤并存：共存并非偶然？
Dermatology. 2010;221(4):320. doi: 10.1159/000318005. Epub 2010 Jan 12.
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Sarcoidosis and melanoma: a referral center study of 1,199 cases.结节病与黑色素瘤：一项对1199例病例的转诊中心研究。
Dermatology. 2009;219(1):25-31. doi: 10.1159/000213245. Epub 2009 Apr 10.