Department of Speech-Language Pathology and Audiology, University of Pretoria, Private bag X20, Hatfield 0028, Pretoria, South Africa.
Department of Speech-Language Pathology and Audiology, University of Pretoria, Private bag X20, Hatfield 0028, Pretoria, South Africa.
Auris Nasus Larynx. 2020 Jun;47(3):367-376. doi: 10.1016/j.anl.2019.11.006. Epub 2019 Dec 18.
Even though there is an association between hearing loss and human immunodeficiency virus (HIV), particularly in low- and middle-income countries, further research is needed to investigate the nature of such hearing loss. Likewise, despite documented vestibular alterations in people with HIV, the true occurrence, presentation, and nature of these manifestations are yet to be established. Advances in technology for vestibular testing has allowed for objective site-of-lesion tests such as the video head impulse test (vHIT), cervical vestibular evoked myogenic potentials (cVEMPs) and ocular vestibular evoked myogenic potential (oVEMPs). The current study aimed to compare and describe auditory, vHIT, cVEMPs and oVEMPs findings in adults with and without HIV.
The current study included an HIV positive group (n = 30) and an HIV negative group (n = 30) who underwent an auditory assessment (tympanometry and pure tone audiometry) and objective vestibular assessments.
The occurrence of hearing loss was 53.3% in the HIV positive group compared to 33.3% in the HIV negative group. A higher occurrence of vestibular involvement was documented in the HIV positive group (73.3%) compared to 13.3% in the HIV negative group.
Auditory assessment and objective measures of vestibular end-organ function (vHIT and VEMPs) can be useful to detect sub-clinical alterations. The equipment is mobile and can be performed in any health care setting such as infectious disease clinics for surveillance and monitoring purposes.
尽管听力损失与人类免疫缺陷病毒（HIV）之间存在关联，特别是在中低收入国家，但仍需要进一步研究以调查这种听力损失的性质。同样，尽管有文献记载 HIV 感染者存在前庭改变，但这些表现的真实发生、表现和性质仍有待确定。前庭测试技术的进步使得能够进行客观的病变部位测试，如视频头脉冲测试（vHIT）、颈性前庭诱发肌源性电位（cVEMPs）和眼性前庭诱发肌源性电位（oVEMPs）。本研究旨在比较和描述 HIV 阳性和阴性成人的听觉、vHIT、cVEMPs 和 oVEMPs 发现。
本研究包括 HIV 阳性组（n=30）和 HIV 阴性组（n=30），他们接受了听觉评估（鼓室压测量和纯音听力测试）和客观前庭评估。
HIV 阳性组听力损失的发生率为 53.3%，而 HIV 阴性组为 33.3%。HIV 阳性组记录到更高的前庭受累发生率（73.3%），而 HIV 阴性组为 13.3%。
听觉评估和前庭终器功能的客观测量（vHIT 和 VEMPs）可用于检测亚临床改变。该设备便携，可在任何医疗保健环境中进行，如传染病诊所，用于监测和监测目的。
