Skowasch D, Gaertner F, Marx N, Meder B, Müller-Quernheim J, Pfeifer M, Schrickel J W, Yilmaz A, Grohé C
Universitätsklinikum Bonn, Medizinische Klinik und Poliklinik II, Sektion Pneumologie, Bonn.
Universitätsklinikum Bonn, Klinik und Poliklinik für Nuklearmedizin, Bonn.
Pneumologie. 2020 Jan;74(1):24-34. doi: 10.1055/a-1031-4588. Epub 2019 Dec 20.
Sarcoidosis is a multisystemic granulomatous disorder which affects the respiratory system in the majority of the cases. Symptomatic cardiac manifestations are found in less than 10 % of the affected cohorts and show a large heterogeneity based on the ethnic background. Cardiac sarcoidosis is not only found in patients with rhythmogenic heart disease, such as atrial and ventricular fibrillation but also in all phenotypes of cardiomyopathy. The overall morbidity and mortality caused by cardiac sarcoidosis in Germany remains unclear and large prospective international observational studies.underline the importance of this disease entity. This consensus paper on diagnostic and therapeutic algorithms for cardiac sarcoidosis is based on a current literature search and forms an expert opinion statement under the auspices of the German Respiratory Society and the German Cardiac Society. The rationale of this statement is to provide algorithms to facilitate clinical decision-making based on the individual case situation.
结节病是一种多系统肉芽肿性疾病，在大多数病例中会影响呼吸系统。有症状的心脏表现见于不到10%的受累人群，并且根据种族背景存在很大的异质性。心脏结节病不仅见于患有节律性心脏病（如心房颤动和心室颤动）的患者，也见于心肌病的所有表型。在德国，心脏结节病导致的总体发病率和死亡率仍不明确，大型前瞻性国际观察性研究强调了这一疾病实体的重要性。这篇关于心脏结节病诊断和治疗算法的共识文件基于当前的文献检索，并在德国呼吸学会和德国心脏学会的支持下形成了专家意见声明。该声明的基本原理是提供算法，以便根据个体病例情况促进临床决策。
