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手术与非手术治疗股骨髋臼撞击综合征:短期疗效的荟萃分析。

Operative Versus Nonoperative Treatment of Femoroacetabular Impingement Syndrome: A Meta-analysis of Short-Term Outcomes.

机构信息

Young Adult Hip Innovation Program, University of Toronto Orthopaedic Sports Medicine, Women's College Hospital, University of Toronto, and Mount Sinai Hospital, Toronto, Ontario, Canada; Department of Paediatrics, University of Toronto, and Mount Sinai Hospital, Toronto, Ontario, Canada.

Young Adult Hip Innovation Program, University of Toronto Orthopaedic Sports Medicine, Women's College Hospital, University of Toronto, and Mount Sinai Hospital, Toronto, Ontario, Canada.

出版信息

Arthroscopy. 2020 Jan;36(1):263-273. doi: 10.1016/j.arthro.2019.07.025.

Abstract

PURPOSE

To compare the outcomes of patients with femoroacetabular impingement (FAI) syndrome treated with hip arthroscopy versus those treated with physical therapy alone.

METHODS

The PubMed, Embase, and Cochrane Library databases were searched from inception to February 15, 2019. All randomized controlled trials (RCTs) that compared operative versus nonoperative treatment in the management of FAI for a minimum 6-month follow-up period were included. The primary outcome was the International Hip Outcome Tool 33. The CLEAR NPT (Checklist to Evaluate a Report of a Nonpharmacological Trial) was used to evaluate the methodologic quality of included studies.

RESULTS

Three RCTs (Level I) were included with a total of 650 patients (323 randomized to surgery and 327 randomized to physical therapy), follow-rate of 90% (583 patients, 295 operative and 288 nonoperative), and average of 11.5 months' follow-up. Regarding participation, 222 of 350 patients (63%) in the FAIT (Femoroacetabular Impingement Trial) study, 348 of 648 (54%) in the FASHIoN (Full UK RCT of Arthroscopic Surgery for Hip Impingement Versus Best Conservative Care) study, and 80 of 104 (77%) in the study by Mansell et al. agreed to participate. The mean age was 35 years, and 51.5% of patients were male patients. All 3 RCTs represented high methodologic quality and a low risk of bias. The frequency-weighted mean follow-up period was 10 months. A meta-analysis of the 3 randomized trials showed that patients treated with operative management had improved preoperative-to-postoperative change scores on the International Hip Outcome Tool 33 compared with the nonoperative group (standardized mean difference, 3.46; 95% confidence interval, 0.07-6.86; P < .05). One study reported on the achievement of clinically relevant outcomes at the individual level, with 51% of the operative group and 32% of the nonoperative group achieving the minimal clinically important difference and with 48% and 19%, respectively, achieving the patient acceptable symptomatic state for the Hip Outcome Score-Activities of Daily Living.

CONCLUSIONS

The results of this meta-analysis show that patients with FAI syndrome treated with hip arthroscopy have statistically superior hip-related outcomes in the short term compared with those treated with physical therapy alone.

LEVEL OF EVIDENCE

Level I, meta-analysis of Level I RCTs.

摘要

目的

比较髋关节镜治疗与单纯物理治疗对股骨髋臼撞击综合征(FAI)患者的疗效。

方法

从建库至 2019 年 2 月 15 日,检索 PubMed、Embase 和 Cochrane Library 数据库。纳入比较手术与非手术治疗 FAI 至少 6 个月随访的随机对照试验(RCT)。主要结局为国际髋关节结局工具 33 评分。采用 CLEAR NPT(非药物试验报告评估清单)评价纳入研究的方法学质量。

结果

纳入 3 项 RCT(Ⅰ级),共 650 例患者(323 例手术,327 例物理治疗),随访率 90%(583 例,295 例手术,288 例非手术),平均随访 11.5 个月。关于参与情况,FAIT(股骨髋臼撞击试验)研究中 350 例患者的 222 例(63%)、FASHIoN(髋关节撞击症关节镜手术与最佳保守治疗的全英 RCT)研究中 648 例患者的 348 例(54%)、Mansell 等研究中 104 例患者的 80 例(77%)同意参与。平均年龄 35 岁,51.5%为男性。所有 3 项 RCT 均具有较高的方法学质量和低偏倚风险。加权均数随访时间为 10 个月。3 项 RCT 的荟萃分析显示,与非手术组相比,手术组的国际髋关节结局工具 33 评分术前至术后的改善程度更高(标准化均数差,3.46;95%置信区间,0.07-6.86;P<.05)。1 项研究报告了个体水平的临床相关结局,手术组的 51%和非手术组的 32%达到了最小临床重要差异,分别有 48%和 19%达到髋关节结局评分-日常活动的患者可接受的症状状态。

结论

该荟萃分析结果表明,与单纯物理治疗相比,髋关节镜治疗 FAI 综合征患者在短期内髋关节相关结局更优。

证据等级

Ⅰ级,Ⅰ级 RCT 的荟萃分析。

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