双重抑制肾素-血管紧张素-醛固酮系统对心血管和肾脏结局的影响：平衡风险和获益。
Effects of dual inhibition of renin-angiotensin-aldosterone system on cardiovascular and renal outcomes: balancing the risks and the benefits.
机构信息
Hypertension Unit, Division of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital, University of Rome Sapienza, Rome, Italy.
IRCCS Neuromed, Pozzilli, IS, Italy.
出版信息
Intern Emerg Med. 2020 Apr;15(3):373-379. doi: 10.1007/s11739-019-02257-3. Epub 2019 Dec 21.
Chronic kidney disease is a worldwide health problem often burdened by severe cardiovascular complications. Hypertension represents one of the most important risk factor in affecting cardiovascular profile of chronic kidney disease patients. Since renin-angiotensin-aldosterone system plays a major role in determining cardiovascular outcome, guidelines recommend the use of renin-angiotensin-aldosteron inhibitors in order to control hypertension.
慢性肾脏病是一个全球性的健康问题，常伴有严重的心血管并发症。高血压是影响慢性肾脏病患者心血管状况的最重要危险因素之一。由于肾素-血管紧张素-醛固酮系统在决定心血管结局方面起着重要作用，指南建议使用肾素-血管紧张素-醛固酮抑制剂来控制高血压。
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