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动静脉内瘘形成术后双功超声检查结果:一项单中心实际经验。

Outcomes of post-operative duplex ultrasound following arteriovenous fistula formation: A pragmatic single-centre experience.

作者信息

Nickinson Andrew To, Rogers Rebecca, Elbasty Ahmed, Nunney Ian, Bennett Philip C

机构信息

Department of Vascular Surgery, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK.

Department of Nephrology, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK.

出版信息

J Vasc Access. 2020 Sep;21(5):623-629. doi: 10.1177/1129729819896226. Epub 2019 Dec 22.

Abstract

BACKGROUND

Duplex ultrasound surveillance with pre-emptive treatment of an identified stenosis is increasingly being utilised to help maintain arteriovenous fistula patency. This study aims to determine whether post-operative duplex ultrasound surveillance can improve fistula patency at 12 months and improve the proportion of 'pre-haemodialysis' patients commencing haemodialysis via a usable fistula.

METHODS

All arteriovenous fistulae formed between 1st January 2015 and 31st August 2017 in a single, tertiary vascular centre were included. Primary and secondary patency at 12 months, along with the proportion of pre-haemodialysis patients commencing haemodialysis via a usable arteriovenous fistula, were compared between the fistulae undergoing duplex ultrasound surveillance and 'standard practice'.

RESULTS

Two hundred forty-one arteriovenous fistulae were created in 216 patients. A higher proportion of brachiobasilic transposition arteriovenous fistula and patients undergoing arteriovenous fistula creation following a previously failed access were identified in the duplex ultrasound surveillance group. Primary patency at 12 months (hazard ratio = 0.43, 95% confidence interval = 0.30-0.61, p < .001) was significantly lower in the duplex ultrasound surveillance group compared with the 'standard practice' group. Despite this, no difference was identified in secondary patency at 12 months (hazard ratio = 1.82, 95% confidence interval = 0.87-3.80, p = .112). No difference was also identified in the proportion of pre-haemodialysis patients starting haemodialysis with a usable arteriovenous fistula (duplex ultrasound surveillance = 65.0% vs standard practice = 77.8%; odds ratio = 0.53, 95% confidence interval 0.58-1.19, p = .279).

CONCLUSION

Post-operative duplex ultrasound surveillance following arteriovenous fistula formation is associated with higher rates of post-operative intervention; however, this does not translate into improved secondary patency or the proportion of pre-haemodialysis patients commencing HD via their fistula.

摘要

背景

采用双功超声监测并对已识别的狭窄进行预防性治疗,越来越多地被用于帮助维持动静脉内瘘的通畅。本研究旨在确定术后双功超声监测是否能提高12个月时内瘘的通畅率,并提高“血液透析前”患者通过可用内瘘开始血液透析的比例。

方法

纳入2015年1月1日至2017年8月31日在单一的三级血管中心形成的所有动静脉内瘘。比较接受双功超声监测的内瘘和“标准治疗”的内瘘在12个月时的初级和次级通畅率,以及血液透析前患者通过可用动静脉内瘘开始血液透析的比例。

结果

216例患者共创建了241个动静脉内瘘。在双功超声监测组中,肱动脉-贵要静脉转位动静脉内瘘和先前血管通路失败后接受动静脉内瘘创建的患者比例更高。与“标准治疗”组相比,双功超声监测组12个月时的初级通畅率(风险比=0.43,95%置信区间=0.30-0.61,p<0.001)显著更低。尽管如此,12个月时的次级通畅率没有差异(风险比=1.82,95%置信区间=0.87-3.80,p=0.112)。血液透析前患者通过可用动静脉内瘘开始血液透析的比例也没有差异(双功超声监测=65.0%,标准治疗=77.8%;优势比=0.53,95%置信区间0.58-1.19,p=0.279)。

结论

动静脉内瘘形成后的术后双功超声监测与更高的术后干预率相关;然而,这并没有转化为更好的次级通畅率或血液透析前患者通过内瘘开始血液透析的比例。

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