成人胃母细胞瘤——罕见癌症中的罕见病例——一例报告及文献复习
Gastroblastoma in Adulthood-A Rarity among Rare Cancers-A Case Report and Review of the Literature.
作者信息
Centonze Giovanni, Mangogna Alessandro, Salviato Tiziana, Belmonte Beatrice, Cattaneo Laura, Monica Melissa Anna Teresa, Garzone Giovanna, Brambilla Cecilia, Pellegrinelli Alessio, Melotti Flavia, Testi Adele, Monti Valentina, Kankava Ketevani, Gasparini Patrizia, Dagrada Gianpaolo, Mazzaferro Vincenzo, Cotsoglou Christian, Collini Paola, Pruneri Giancarlo, Milione Massimo
机构信息
Clinical Research Lab, Department of Pathology and Laboratory Medicine, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
Tumor Genomics Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
出版信息
Case Rep Pathol. 2019 Nov 28;2019:4084196. doi: 10.1155/2019/4084196. eCollection 2019.
Gastroblastoma (GB) is a rare gastric epithelial-mesenchymal neoplasm, first described by Miettinen et al. So far, all reported cases described the tumor in children or young adults, and similarities with other childhood blastomas have been postulated. We report a case of GB in a 43-year-old patient with long follow up and no recurrence up to 100 months after surgery. So far, this is the second case of GB occurring in the adult age >40-year-old. Hence, GB should be considered in the differential diagnosis of microscopically comparable conditions in adults carrying a worse prognosis and different clinical approach.
胃母细胞瘤（GB）是一种罕见的胃上皮-间充质肿瘤，由米耶蒂宁等人首次描述。迄今为止，所有报道的病例均为儿童或青年患者，且推测其与其他儿童母细胞瘤存在相似之处。我们报告一例43岁胃母细胞瘤患者，术后随访长达100个月，无复发。迄今为止，这是第二例发生在40岁以上成年人中的胃母细胞瘤。因此，对于预后较差且临床处理方式不同的成年人中显微镜下表现相似的情况，鉴别诊断时应考虑胃母细胞瘤。
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