纽约市静脉注射吸毒者中与严重HIV-1相关疾病的更大范围情况。

A larger spectrum of severe HIV-1--related disease in intravenous drug users in New York City.

作者信息

Stoneburner R L, Des Jarlais D C, Benezra D, Gorelkin L, Sotheran J L, Friedman S R, Schultz S, Marmor M, Mildvan D, Maslansky R

机构信息

AIDS Research Unit, New York City Department of Health, NY 10013.

出版信息

Science. 1988 Nov 11;242(4880):916-9. doi: 10.1126/science.3187532.

DOI:10.1126/science.3187532

PMID:3187532

Abstract

Increasing mortality in intravenous (IV) drug users not reported to surveillance as acquired immunodeficiency syndrome (AIDS) has occurred in New York City coincident with the AIDS epidemic. From 1981 to 1986, narcotics-related deaths increased on average 32% per year from 492 in 1981 to 1996 in 1986. This increase included deaths from AIDS increasing from 0 to 905 and deaths from other causes, many of which were infectious diseases, increasing from 492 to 1091. Investigations of these deaths suggest a causal association with human immunodeficiency virus (HIV) infection. These deaths may represent a spectrum of HIV-related disease that has not been identified through AIDS surveillance and has resulted in a large underestimation of the impact of AIDS on IV drug users and blacks and Hispanics.

摘要

在纽约市，与艾滋病流行同时出现的情况是，静脉注射吸毒者中未作为获得性免疫缺陷综合征（艾滋病）上报至监测系统的死亡率不断上升。1981年至1986年期间，与麻醉品相关的死亡人数平均每年增加32%，从1981年的492例增至1986年的1996例。这种增加包括艾滋病死亡人数从0增至905例，以及其他原因导致的死亡人数从492例增至1091例，其中许多是传染病。对这些死亡病例的调查表明与人类免疫缺陷病毒（HIV）感染存在因果关联。这些死亡可能代表了一系列与HIV相关的疾病，而这些疾病尚未通过艾滋病监测得以识别，从而导致对艾滋病对静脉注射吸毒者以及黑人和西班牙裔人群影响的严重低估。