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[分层厚度头皮与同种异体脱细胞真皮基质修复特大面积烧伤患者手部深度创面]

[Split-thickness scalp and allogenic acellular dermal matrix in repairing deep wounds of hands in patients with extremely extensive burns].

作者信息

Guo H L, Ling X W, Liu Z J, Xu J J, Lin C, Lu C J

机构信息

Department of Burns and Wound Center, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.

出版信息

Zhonghua Shao Shang Za Zhi. 2019 Dec 20;35(12):876-878. doi: 10.3760/cma.j.issn.1009-2587.2019.12.009.

Abstract

To explore the clinical effects of split-thickness scalp and allogenic acellular dermal matrix (ADM) in repairing deep wounds of hands in patients with extremely extensive burns. Six patients with extremely extensive burns complicated by deep burn in hands were admitted to our department from December 2014 to December 2017, including 4 males and 2 females, aged 21 to 58 years. Their total burn areas were from 85% to 95% total body surface area (TBSA), and the sum of deep-partial thickness and full-thickness wounds was larger than 50% TBSA. Under general anesthesia, deep wounds of 10 dorsal hands were repaired by combined transplantation of split-thickness scalp and allogenic ADM in 4 to 6 weeks after injury. The skin grafting range was beyond the metacarpophalangeal joint, including partial dorsal digital deep wounds. Survival of skin grafts on dorsal hands, follow-up of hand shape and functional recovery were observed and recorded. Six patients were successfully treated. There was no infection on the dorsal deep wounds of 10 hands after surgery, and the grafts survived well. During follow-up of 1 to 2 years after operation, there were no recurrent tension blisters or dorsal extension deformity of the metacarpophalangeal joints in 10 hands, the shape and function of hands recovered well, and hand Carroll scores were from 90 to 99 points, with functional levels of Ⅴ and Ⅵ. The combined transplantation of split-thickness scalp and allogenic ADM is a good method for repairing deep hand wounds in patients with extremely extensive burns, which can alleviate the cicatrix hyperplasia and contracture of healed hand wounds, and improve the shape and function of hands.

摘要

探讨微粒皮与异体脱细胞真皮基质(ADM)联合移植修复特大面积烧伤患者手部深度创面的临床效果。2014年12月至2017年12月,我科收治6例特大面积烧伤合并手部深度烧伤患者,其中男4例,女2例,年龄21~58岁。烧伤总面积85%~95%总体表面积(TBSA),深Ⅱ度及Ⅲ度创面之和大于50%TBSA。伤后4~6周,在全身麻醉下,采用微粒皮与异体ADM联合移植修复10只手背深度创面。植皮范围超过掌指关节,包括部分指背深部创面。观察并记录手背植皮成活情况、手部外形及功能恢复情况。6例患者均治疗成功。术后10只手背深部创面均未发生感染,植皮成活良好。术后随访1~2年,10只手均未出现复发性张力性水疱及掌指关节背伸畸形,手部外形及功能恢复良好,手部Carroll评分90~99分,功能等级为Ⅴ级和Ⅵ级。微粒皮与异体ADM联合移植是修复特大面积烧伤患者手部深度创面的一种良好方法,可减轻手部创面愈合后的瘢痕增生及挛缩,改善手部外形及功能。

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