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帕金森病与重症肌无力患者——三例新病例报告及文献综述

Patients with Parkinson's Disease and Myasthenia Gravis-A Report of Three New Cases and Review of the Literature.

作者信息

Odajiu Irina, Davidescu Eugenia Irene, Mitu Cristina, Popescu Bogdan Ovidiu

机构信息

Neurology Department, Colentina Clinical Hospital, 020125 Bucharest, Romania.

Department of Clinical Neurosciences, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.

出版信息

Medicina (Kaunas). 2019 Dec 23;56(1):5. doi: 10.3390/medicina56010005.

Abstract

Neurodegenerative diseases such as Parkinson's disease (PD)have increasing incidence, due to lifespan expansion. The association between PD and Myasthenia Gravis (MG) is uncommon, and so far, since 1987, 26 cases have been reported. We report here a series of three new cases, two men and one woman with this peculiar combination of conditions, identified in the Neurology Department of Colentina Clinical Hospital. In this article, the pathogenesis of MG in patients with PD is discussed, along with a literature review regarding the co-occurrence of these two neurological diseases.

摘要

诸如帕金森病(PD)之类的神经退行性疾病,由于寿命延长,发病率日益上升。PD与重症肌无力(MG)之间的关联并不常见,截至目前,自1987年以来,已报告26例病例。我们在此报告在科伦蒂纳临床医院神经科发现的一系列3例新病例,其中2名男性和1名女性患有这种特殊的病症组合。本文讨论了PD患者中MG的发病机制,并对这两种神经疾病的共现情况进行了文献综述。

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