广泛性骨盆切除术在复发性卵巢腺癌二线细胞减灭术中的应用。
Extended Pelvic Resections as Part of Secondary Cytoreduction for Relapsed Ovarian Adenocarcinoma.
机构信息
"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
"I. Cantacuzino" Clinical Hospital, Bucharest, Romania.
出版信息
In Vivo. 2020 Jan-Feb;34(1):397-400. doi: 10.21873/invivo.11787.
BACKGROUND/AIM: Ovarian cancer presents an aggressive tumor biology, a significant number of patients experiencing recurrent disease. The aim of this study was to examine the feasibility and effectiveness of secondary debulking surgery for relapsed ovarian cancer.
PATIENTS AND METHODS
Between 2014 and 2018, debulking surgery for relapsed ovarian cancer was performed in 40 cases.
RESULTS
Debulking surgery to no residual disease was achieved in 31 cases; among the remaining cases, an R1 resection was feasible in six cases, while in the remaining three cases an R2 resection was performed. The most commonly performed visceral resections were represented by rectosigmoidian resection, right colon resection, total or partial cystectomy and unilateral or bilateral ureteral resection. The early postoperative morbidity rate was 32.5% while the postoperative mortality rate was 2.5%.
CONCLUSION
Extended pelvic resections are feasible in patients with relapsed ovarian cancer and might be performed with acceptable rates of postoperative complications.
背景/目的：卵巢癌具有侵袭性的肿瘤生物学特性，相当数量的患者会出现疾病复发。本研究旨在探讨复发性卵巢癌二次肿瘤细胞减灭术的可行性和有效性。
患者与方法
2014 年至 2018 年间，对 40 例复发性卵巢癌患者实施了肿瘤细胞减灭术。
结果
31 例患者达到无残留疾病的肿瘤细胞减灭术；其余病例中，6 例可行 R1 切除术，而另外 3 例则行 R2 切除术。最常进行的内脏切除术包括直肠乙状结肠切除术、右半结肠切除术、全或部分子宫切除术和单侧或双侧输尿管切除术。术后早期并发症发生率为 32.5%，术后死亡率为 2.5%。
结论
对于复发性卵巢癌患者，可进行广泛的盆腔切除术，且术后并发症发生率可接受。
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